How Do You Spell CRYOULTRAMICROTOMY?

Pronunciation: [kɹˌa͡ɪə͡ʊltɹˌama͡ɪkɹˈə͡ʊtəmɪ] (IPA)

"Cryoultramicrotomy" is a term commonly used in pathology and biology that refers to an advanced tissue preparation technique used for electron microscopy. The spelling of this word can be understood using the International Phonetic Alphabet (IPA) transcription, which translates the word as /kraɪoʊˌʌltrəˈmaɪkrətəmi/. The word is broken down into its syllables, with the primary stress on the third syllable (ultra). The prefix "cryo-" means "cold," and "ultramicrotomy" refers to the thin slicing of tissue specimens to such a degree that they can be scanned under a transmission electron microscope.

CRYOULTRAMICROTOMY Meaning and Definition

  1. Cryoultramicrotomy is a specialized technique used in the field of histology and microscopy. It involves the preparation of extremely thin sections of frozen biological samples for examination under an electron microscope. The term "cryo" refers to the use of extreme cold temperatures, usually achieved by rapidly freezing the sample in liquid nitrogen or a similar cryogen. "Ultramicrotomy" refers to the process of cutting very thin slices of the sample.

    In cryoultramicrotomy, the frozen sample is mounted on a cryostat, a device specifically designed for cutting frozen specimens. The cryostat maintains the sample at low temperatures while allowing for precise sectioning. A microtome, a mechanical instrument used for slicing samples, is used to cut the frozen sample into ultra-thin sections.

    The resulting sections are usually between 50 and 500 nanometers in thickness, depending on the specific requirements of the experiment or analysis. These ultrathin slices can then be placed on electron microscope grids for imaging and further analysis.

    Cryoultramicrotomy is advantageous for several reasons. First, the freezing of the sample preserves its integrity and minimizes distortion and artifacts that may occur during traditional sample preparation methods. Second, the ultrathin slices allow for high-resolution imaging under an electron microscope, providing detailed information about the sample's cellular and subcellular structures. Lastly, cryoultramicrotomy is particularly useful for studying delicate or sensitive samples, such as biological tissues or organisms that are prone to damage during traditional preparation techniques.

    Overall, cryoultramicrotomy is an essential technique in the fields of histology and electron microscopy, enabling researchers to explore the intricate details of biological samples with precision and accuracy.

Common Misspellings for CRYOULTRAMICROTOMY

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  • cryiultramicrotomy
  • crykultramicrotomy
  • crylultramicrotomy
  • crypultramicrotomy

Etymology of CRYOULTRAMICROTOMY

The word "Cryoultramicrotomy" is a combination of several elements:

1. "Cryo-" is a prefix derived from the Greek word "kryos", meaning "cold" or "frost". It is often used to indicate a process or technique involving extreme cold temperatures.

2. "Ultra-" is a prefix of Latin origin meaning "beyond" or "extremely". It is commonly used to indicate something that is beyond the normal limit or exceptionally high quality.

3. "Microtomy" is derived from the combination of "micro-" and "-tomy". "Micro-" comes from the Greek word "mikros", meaning "small", and "-tomy" is derived from the Greek word "tomos", meaning "a cutting" or "incision". "Microtomy" refers to the technique of cutting very thin sections, typically for microscopic examination.

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