CREATINASE Meaning and
Definition
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Creatinase is an enzyme that is involved in the metabolism of creatine, a nitrogenous organic acid that is an important component for energy storage in muscles and brain cells. Creatinase catalyzes the hydrolysis of creatine into creatinine, a waste product that is excreted in urine.
Creatinase is primarily produced by bacteria and fungi, and it plays a crucial role in the nitrogen cycle by breaking down creatine and releasing nitrogen. This enzymatic reaction is essential for the degradation of creatine in various environmental settings, as well as in the digestive system of animals.
The enzymatic activity of creatinase is dependent on various factors such as pH, temperature, and the presence of cofactors. Optimum conditions for this enzyme typically range from pH 7 to 9 and temperatures around 40-50 degrees Celsius.
Creatinase is an important enzyme in research and industrial applications. It is commonly utilized in the production of creatinine detection kits, which are used to measure creatinine levels in biological samples. Additionally, creatinase is employed in the production of high-purity creatinine for pharmaceutical purposes.
Understanding the functions and characteristics of creatinase is relevant not only in biological and biochemical research but also in fields such as medicine, sports science, and environmental science. By studying creatinase, scientists can gain valuable insights into the metabolism and breakdown of creatine, thus contributing to the development of diagnostic tools and treatments for certain disorders and diseases.
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A deoxidizing ferment which converts creatine into creatinine.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for CREATINASE
- xreatinase
- vreatinase
- freatinase
- dreatinase
- ceeatinase
- cdeatinase
- cfeatinase
- cteatinase
- c5eatinase
- c4eatinase
- crwatinase
- crsatinase
- crdatinase
- crratinase
- cr4atinase
- cr3atinase
- creztinase
- crestinase
- crewtinase
- creqtinase
Etymology of CREATINASE
The word "creatinase" is derived from two main components: "creatine" and the suffix "-ase".
1. "Creatine": The term "creatine" originated from the Greek word "kreas" meaning "flesh" and the suffix "-ine" indicating a nitrogenous substance. Creatine is a nitrogenous organic compound found in muscle tissue and acts as an energy reservoir in the body.
2. "-ase": The suffix "-ase" is commonly used in biology to denote an enzyme. It comes from the Greek word "άση" (ase), which means "enzyme", and ultimately from the verb "ένζυμον" (enzymon) that means "to ferment".
Combining these parts, "creatinase" can be understood to mean an enzyme involved in the metabolism or breakdown of creatine.
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