COULTER COUNTER Meaning and
Definition
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A Coulter counter is a scientific instrument used for quantifying and sizing cells and other particles present in a fluid sample. It operates based on the principle of electrical impedance. The device consists of a small aperture or tube through which the fluid sample passes, and two electrodes located at either side of the aperture. An electric current is applied across the electrodes, and as the sample flows through the aperture, individual particles disrupt the current flow, causing brief impedance changes. These changes are detected and measured by the instrument.
The Coulter counter is commonly used in fields such as hematology, microbiology, and particle analysis. It enables precise determination of the concentration of cells or particles in a sample, as well as providing size distribution information. By measuring the electrical impedance disturbances caused by each particle, the instrument can differentiate and count various types and sizes of cells or particles within the sample.
The technology behind the Coulter counter has been widely adopted in both laboratory and clinical settings due to its accuracy, reproducibility, and ease of use. It has revolutionized cell counting, allowing for quicker and more accurate analysis, which has significant applications in clinical diagnostics, research, and quality control in various industries. The Coulter counter's ability to rapidly analyze large numbers of particles has contributed to advances in medical diagnostics, pharmaceutical development, and other scientific investigations where particle sizing and counting are crucial.
Common Misspellings for COULTER COUNTER
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Etymology of COULTER COUNTER
The word "Coulter counter" is derived from the name of its inventor, Wallace H. Coulter. Coulter counters are instruments used to count and size particles suspended in a liquid medium, particularly blood cells. They utilize electrical or optical techniques to measure and analyze the particles, and were first developed by Coulter in the 1950s. The term "counter" refers to its ability to count particles, while "Coulter" is a reference to the inventor.
