COS CELL Meaning and
Definition
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COS cell, short for Clonal Origin Sublines cell, refers to a type of cell line that is derived from the CV-1 cell line. The CV-1 cell line is a continuous lineage of monkey kidney fibroblast cells that were originally derived from the kidney tissue of an African green monkey, Cercopithecus aethiops. The COS cell line was developed by transforming the CV-1 cells with an origin-defective mutant of the Simian Virus 40 (SV40), a virus that can infect monkey cells.
COS cells are widely used in molecular biology and biotechnology research as they possess numerous advantageous characteristics. These include the ease of culture and maintenance, high transfection efficiency, and the capability to support the replication of recombinant DNA molecules, particularly those carrying the SV40 origin of replication. This feature enables the production of large amounts of viral vectors or recombinant proteins for various applications.
Moreover, COS cells are often employed in protein expression studies and functional assays due to their ability to efficiently produce and secrete heterologous proteins. They have proven valuable for the production of viral particles and pseudotyped viruses that serve as essential tools in virology research and gene delivery technologies.
In summary, the COS cell line is a widely used and versatile tool in molecular biology and biotechnology due to its ability to efficiently replicate recombinant DNA and produce proteins. With its wide range of applications, the COS cell line continues to contribute to advancements in various scientific fields.
Common Misspellings for COS CELL
- xos cell
- vos cell
- fos cell
- dos cell
- cis cell
- cks cell
- cls cell
- cps cell
- c0s cell
- c9s cell
- coa cell
- coz cell
- cox cell
- cod cell
- cow cell
- cos xell
- cos vell
- cos fell
- cos dell
- cos cwll
