COLONIC AGANGLIONOSIS Meaning and
Definition
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Colonic Aganglionosis, also known as Hirschsprung's disease, is a congenital disorder of the large intestine (colon) characterized by the absence of ganglion cells in various parts of the bowel. Ganglion cells are responsible for controlling the movements of the intestine, particularly for pushing stool forward. In individuals with colonic aganglionosis, these ganglion cells are missing in a section or multiple sections of the colon, causing a disruption in the normal peristaltic movements necessary for the expulsion of waste.
This condition typically presents early in infancy, with symptoms such as difficulty passing stool (constipation), failure to pass meconium (the first stool of a newborn), abdominal distension, and poor weight gain. The absence of ganglion cells leads to an accumulation of stool, causing the affected segment of the colon to become distended and dilated.
Diagnosis of colonic aganglionosis is usually confirmed through various tests, including rectal biopsy, which involves taking a small tissue sample from the rectum to examine the absence of ganglion cells under a microscope. Other imaging studies may also be performed to determine the extent and location of the affected area.
Treatment for colonic aganglionosis typically involves surgical intervention to remove the segment of the colon without ganglion cells and connect the healthy portions together. This helps create a pathway for the normal passage of stool. In some cases, a temporary colostomy (surgical opening in the abdomen) may be necessary to divert stool before the final reconstructive surgery.
Long-term outcomes for individuals with colonic aganglionosis can vary depending on the severity and extent of the condition. With early diagnosis and appropriate treatment, most individuals can lead a normal life with minimal complications. However, ongoing medical management, including
Common Misspellings for COLONIC AGANGLIONOSIS
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Etymology of COLONIC AGANGLIONOSIS
The word "colonic aganglionosis" is a medical term used to describe a condition known as Hirschsprung's disease, which affects the large intestine (colon) and causes problems with bowel movements. The etymology of this term can be broken down as follows:
1. Colonic: Referring to the colon, which is the large intestine. This comes from the Latin word "colon", which means "large intestine" or "water conduit".
2. Aganglionosis: This term consists of two root elements: "a-" and "ganglion-" combined with the suffix "-osis".
- "A-" is a prefix derived from the Greek language, usually indicating "without" or "not".
- "Ganglion" is a Greek word meaning "knot" or "swelling". In medical terminology, it specifically refers to a mass of nerve tissue.
Similar spelling word for COLONIC AGANGLIONOSIS
