How Do You Spell COCARBOXYLASE?

Pronunciation: [kˈɒkɑːbˌɒksɪlˌe͡ɪs] (IPA)

The spelling of the word "cocarboxylase" can be explained through its phonetic transcription in IPA (International Phonetic Alphabet): /kokɑrbɒksɪleɪz/. The first syllable is pronounced with a stress on the "ko" sound, followed by the "car" sound, and then the "box" sound. The second half of the word begins with "yle," which is pronounced as "ile." Finally, the "ase" ending is pronounced with a long "a" sound, followed by the "z" sound. The word cocarboxylase refers to a coenzyme that plays a role in numerous metabolic processes in the body.

COCARBOXYLASE Meaning and Definition

1. Cocarboxylase is a term used in biochemistry to describe a coenzyme form of vitamin B1 known as thiamine pyrophosphate (TPP). It is an essential cofactor for several enzymes involved in carbohydrate metabolism in living organisms, including humans.

   In its active form, cocarboxylase acts as a catalyst for important biochemical reactions, specifically those that involve the decarboxylation of α-keto acids. These reactions are crucial for the conversion of pyruvate, a key intermediate in glucose metabolism, into acetyl-CoA, a molecule that plays a central role in the citric acid cycle, also known as the Krebs cycle. This cycle is responsible for the production of ATP, the cell's main source of energy.

   Cocarboxylase works by binding to enzymes that require its assistance to carry out the decarboxylation reactions. Once bound, it plays a vital role in the transfer of a two-carbon fragment from the substrates to other molecules, thereby participating in various metabolic pathways.

   Overall, cocarboxylase plays a fundamental role in carbohydrate metabolism, ensuring the proper breakdown and utilization of glucose in living organisms. Its deficiency can lead to severe health issues, with symptoms including weakness, fatigue, and impaired neurological function. Conversely, supplementing with cocarboxylase can help overcome vitamin B1 deficiency and support proper cellular energy production.

Common Misspellings for COCARBOXYLASE

• xocarboxylase
• vocarboxylase
• focarboxylase
• docarboxylase
• cicarboxylase
• ckcarboxylase
• clcarboxylase
• cpcarboxylase
• c0carboxylase
• c9carboxylase
• coxarboxylase
• covarboxylase
• cofarboxylase
• codarboxylase
• coczrboxylase
• cocsrboxylase
• cocwrboxylase
• cocqrboxylase
• cocaeboxylase

Etymology of COCARBOXYLASE

The word "cocarboxylase" is formed by combining two components: "co" and "carboxylase".

The prefix "co-" in this context refers to coenzyme, which is a non-protein molecule required by an enzyme to function properly.

The term "carboxylase" comes from the word "carboxyl", which refers to a functional group (-COOH) consisting of a carbon atom attached to an oxygen atom by a double bond and to a hydroxyl group (-OH) by a single bond. In the context of enzymes, carboxylase specifically refers to an enzyme that catalyzes the addition or removal of a carboxyl group.

Therefore, "cocarboxylase" refers to a coenzyme that is involved in carboxylation reactions, where a carboxyl group is added or removed as part of a chemical reaction.

Plural form of COCARBOXYLASE is COCARBOXYLASES