COBALT ENOLASE Meaning and
Definition
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Cobalt enolase is a metalloenzyme that belongs to the enolase family of enzymes. Enolases are essential for the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP) during the glycolytic pathway. Cobalt enolase is a variant of the traditional enolase enzyme, where cobalt (Co) is substituted for the more commonly found metal ion, magnesium (Mg), in the active site.
The substitution of cobalt in place of magnesium alters the properties and activity of the enzyme. Cobalt enolase still functions to catalyze the reversible conversion of 2-PG to PEP, but with different efficiencies and kinetics compared to the magnesium-containing form. This alteration in activity and behavior makes cobalt enolase a useful tool in various biochemical and biotechnological applications.
Cobalt enolase is typically obtained through biochemical methods, where magnesium ions present in the wild-type enzyme are exchanged with cobalt using chemical chelation techniques. This modification enables researchers to study the effects of metal substitution on enzyme function and catalysis. Furthermore, cobalt enolase has been utilized in various biotechnological processes due to its altered reactivity, stability, and potential for novel catalytic properties.
In summary, cobalt enolase is a variant of the classical enolase enzyme that replaces the active site metal ion, magnesium, with cobalt. This substitution modifies the enzyme's activity and behavior, making it a valuable tool for studying enzyme function as well as for potential biotechnological applications.
Common Misspellings for COBALT ENOLASE
- xobalt enolase
- vobalt enolase
- fobalt enolase
- dobalt enolase
- cibalt enolase
- ckbalt enolase
- clbalt enolase
- cpbalt enolase
- c0balt enolase
- c9balt enolase
- covalt enolase
- conalt enolase
- cohalt enolase
- cogalt enolase
- cobzlt enolase
- cobslt enolase
- cobwlt enolase
- cobqlt enolase
- cobakt enolase
- cobapt enolase
Etymology of COBALT ENOLASE
The word "Cobalt Enolase" comes from the combination of two terms: "cobalt" and "enolase".
1. Cobalt: The term "cobalt" refers to a chemical element with the symbol Co and atomic number 27. It was named after the German word "kobold", which means "goblin" or "elf" and was used by miners to describe troublesome ores that looked like other metals but yielded none. The name "kobold" eventually evolved to "Cobalt".
2. Enolase: Enolase is an enzyme that is involved in the metabolic pathway known as glycolysis. The term "enolase" is derived from its function.
