CMH Meaning and
Definition
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CMH stands for Centimorgan Haldane, a unit used to measure genetic distance between two loci or genes on a chromosome. It is named after the British geneticist John Burdon Sanderson Haldane and the French geneticist Alfred Henry Sturtevant. 1 CMH corresponds to a recombination frequency of 1% between two loci.
Recombination is the process by which new combinations of genetic material are formed. It occurs during sexual reproduction, where chromosomes from each parent exchange segments. The frequency of recombination between two loci is influenced by their physical distance from each other on the chromosome. The longer the distance between two loci, the more likely a recombination event will occur, resulting in a greater genetic distance measured in CMH.
The use of CMH as a unit of genetic distance allows researchers to estimate the likelihood of recombination events between loci on a chromosome. It provides valuable information for genetic mapping and linkage analysis studies, aiding in the identification and understanding of genes associated with certain diseases or traits.
In summary, CMH is a unit of genetic distance that represents the likelihood of recombination events between loci on a chromosome. It plays a crucial role in genetic research, particularly in the field of genetic mapping and understanding inheritance patterns.
Common Misspellings for CMH
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