CLOFAZIMINE Meaning and
Definition
-
Clofazimine is a pharmaceutical compound belonging to the class of drugs called riminophenazines. It is mainly used as an antibacterial medication in the treatment of various types of infections, particularly leprosy (Hansen's disease). The drug has demonstrated antimicrobial activity against Mycobacterium leprae, the bacteria responsible for causing leprosy, as well as other mycobacterial species.
The mechanism of action of clofazimine is not completely understood, but it is known to have bactericidal properties. It is believed to exert its antimicrobial effects by binding to bacterial DNA and inhibiting the synthesis of RNA and protein, thereby interfering with vital cellular processes. Additionally, clofazimine is known to disrupt the integrity of microbial membranes, leading to a leakage of cellular components and subsequent bacterial cell death.
Clofazimine is available in capsule form for oral administration. It is usually used in combination with other anti-leprosy drugs to enhance treatment efficacy and prevent the development of bacterial resistance. The drug has a long half-life, allowing for once-daily dosing. Adverse effects associated with clofazimine include discoloration of the skin, eyes, and bodily fluids (which is reversible upon discontinuation), gastrointestinal symptoms, and increased sensitivity to sunlight.
In summary, clofazimine is an antibiotic drug primarily employed for the management of leprosy and other mycobacterial infections. It works by inhibiting essential bacterial processes and damaging cell membranes, leading to the eradication of the causative bacteria.
Common Misspellings for CLOFAZIMINE
- xlofazimine
- vlofazimine
- flofazimine
- dlofazimine
- ckofazimine
- cpofazimine
- coofazimine
- clifazimine
- clkfazimine
- cllfazimine
- clpfazimine
- cl0fazimine
- cl9fazimine
- clodazimine
- clocazimine
- clovazimine
- clogazimine
- clotazimine
- clorazimine
- clofzzimine
Etymology of CLOFAZIMINE
The word "Clofazimine" has a relatively straightforward etymology.
"Clofazimine" is derived from a combination of two parts:
1. "Clo-" is derived from "chlorine". This prefix indicates the presence of chlorine in the chemical structure of the compound.
2. "-fazimine" is derived from the second part of the name "azimine". The suffix "-azimine" is commonly used in pharmaceutical nomenclature to indicate a class of compounds known as amines.
Therefore, "Clofazimine" can be understood to mean a compound that contains chlorine and belongs to the class of amines. This is appropriate as clofazimine is an antibiotic drug used in the treatment of leprosy and other infectious diseases.
Similar spelling word for CLOFAZIMINE
Infographic
Add the infographic to your website:
