How Do You Spell CICLOSPORIN?

Pronunciation: [sˈɪkləspˌɔːɹɪn] (IPA)

Ciclosporin is a medication used to prevent organ transplant rejection and treat various autoimmune disorders. Its spelling may seem confusing, but it can be easily explained with IPA phonetic transcription. The first syllable, "ci", is pronounced as "sɪ", similar to the word "sit". The second syllable, "clo", is pronounced as "kloʊ", similar to the word "clover". The third syllable, "spo", is pronounced as "spoʊ", similar to the word "spore". The final syllable, "rin", is pronounced as "rɪn", similar to the word "grin". Thus, Ciclosporin is pronounced as "sɪkloʊsporɪn".

CICLOSPORIN Meaning and Definition

1. Ciclosporin, also known as cyclosporine, is an immunosuppressive drug that plays a crucial role in preventing transplant rejection and managing certain autoimmune conditions. It is a cyclic peptide made up of eleven amino acids and was initially isolated from the fungus Tolypocladium inflatum in the late 1970s.

   Ciclosporin works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. By suppressing T-cell activation, it helps to prevent the immune system from attacking and rejecting transplanted organs, such as kidneys, liver, or heart. Additionally, it is used in the treatment of various autoimmune diseases like rheumatoid arthritis, psoriasis, and atopic dermatitis, where it helps to reduce inflammation and minimize the adverse effects of an overactive immune system.

   The drug is typically administered orally or intravenously under medical supervision, as its dosage depends on various factors such as the patient's condition, weight, and response to treatment. However, it is essential to monitor and adjust the dosage regularly to maintain therapeutic levels and minimize potential side effects. Some common side effects associated with ciclosporin include high blood pressure, kidney damage, increased susceptibility to infections, and an elevated risk of certain types of cancer.

   Due to its potent immunosuppressive properties, ciclosporin has revolutionized the field of organ transplantation, significantly improving the success rates of these procedures. However, it is essential to use this medication only under strict medical supervision to balance its benefits and potential risks.

Common Misspellings for CICLOSPORIN

• ciclosporiun

Etymology of CICLOSPORIN

The word "Ciclosporin" is derived from several sources. The "ciclo" component comes from "cicloheximide", which is an antifungal and antiviral compound. The "spor" component comes from "sporadic", indicating that the drug is not constant or continuous. Lastly, the "-in" ending is a common suffix used in the names of pharmaceutical drugs. Therefore, the word "Ciclosporin" combines these elements to create a unique name for this immunosuppressive drug.