The word "chromophobe" refers to a cell or tissue that does not absorb or bind to a particular stain or dye. It is pronounced /krəʊmə(ʊ)ˌfəʊb/, with the stress on the second syllable. The IPA phonetic transcription shows that the "ch" sound is pronounced as a voiceless velar fricative, followed by the "r" sound. The second syllable is pronounced as "muh-oh," with the stress on the first vowel. The final syllable features the "f" sound followed by the voiced "b."
Chromophobe is a term used in biology and medicine to refer to a type of cell or tissue that lacks pigment or color. Derived from the Greek words "chromo," meaning color, and "phobos," meaning fear or aversion, the term essentially describes cells or tissues that do not show a specific affinity for staining or pigmentation.
In the field of histology and pathology, chromophobe cells often appear pale or translucent under microscopic examination, since they do not readily absorb or retain dyes or stains compared to other cells. This characteristic makes them challenging to visualize and differentiate from surrounding tissues.
The term "chromophobe" is commonly applied to specific cell types found in various biological structures, such as the anterior pituitary gland and the kidneys. In the anterior pituitary gland, chromophobes refer to hormone-producing cells that lack hormone granules and are usually considered non-functional. In the kidneys, chromophobe cells pertain to a type of renal cell carcinoma that typically displays low-grade malignancy and less pigmentation compared to other types of kidney cancer.
Overall, chromophobe describes cells or tissues that appear devoid of color or pigmentation and exhibit reduced affinity for staining. The term's usage primarily revolves around its application in histology, pathology, and medical disciplines, aiding in the classification and identification of specific cell types or diseases.
The word "chromophobe" is derived from the Greek roots "chromo-" meaning color, and "phobos" meaning fear or aversion.