How Do You Spell CHOROIDEREMIA?

Pronunciation: [kˌɔːɹɔ͡ɪdəɹˈiːmi͡ə] (IPA)

Choroideremia is a genetic disorder that affects the retina, resulting in progressive vision loss. The spelling of this word can be broken down into its phonetic components using the IPA transcription system. The first syllable, "cho," is pronounced as /kɔ/, while the second syllable, "roi," is pronounced as /rɔɪ/. The final syllable, "deremia," is pronounced as /dɛrəmiə/. Altogether, the correct pronunciation of choroideremia is /kɔːrɔɪdɛriːmiə/. Understanding the phonetics of medical terms is important for clear communication between doctors, patients, and caregivers.

CHOROIDEREMIA Meaning and Definition

1. Choroideremia is a rare genetic disorder that primarily affects the eyes, specifically the retina and choroid. The choroid is the layer of blood vessels that provides oxygen and nutrients to the retina, which is responsible for transmitting visual signals to the brain.

   Individuals with choroideremia typically begin to experience vision loss in late childhood or early adulthood. This progressive loss of vision is due to the gradual degeneration and atrophy of the retina and choroid. Initially, individuals may have difficulty seeing at night or in low light conditions. As the disorder progresses, loss of peripheral vision occurs, resulting in tunnel vision. Eventually, central vision can also be affected, leading to significant visual impairment or blindness.

   Choroideremia is caused by mutations in the CHM gene, which provides instructions for the production of a protein necessary for normal functioning of the cells in the retina and choroid. The inheritance pattern of this disorder is X-linked recessive, which means it primarily affects males, while females are typically carriers of the genes and exhibit milder symptoms or may be unaffected.

   Although there is currently no cure for choroideremia, researchers are exploring potential treatment options, including gene therapy and stem cell therapy. Supportive measures such as low vision aids, orientation and mobility training, and psychological support can help individuals with choroideremia adapt to their vision loss and maintain a good quality of life. Genetic counseling is also important for affected individuals and their families to understand the risks and options for future pregnancies.

2. Absence of the chorioid coat of the eye.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for CHOROIDEREMIA

• choroideremiw

Etymology of CHOROIDEREMIA

The word "Choroideremia" is derived from Greek roots.

The term "choroid" comes from the Greek word "choroeidḗs" (χοροειδής), meaning "like a chorion". The choroid is a vascular layer of the eye that lies between the retina and the sclera.

"Erēmos" (ἔρημος) is a Greek word meaning "desert" or "desolate", and the suffix "-ia" in medical terminology often indicates a disease or condition. The term "choroideremia" is used to describe a rare genetic eye disorder characterized by progressive degeneration of the choroid, leading to loss of vision.

Therefore, the etymology of "Choroideremia" refers to the degeneration of the choroid, which is a key characteristic of the disease.