CHOLYLGLYCINE Meaning and
Definition
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Cholylglycine, also known as glycocholic acid or glycocholate, is a bile acid compound derived from cholesterol and glycine. It is naturally produced in the liver and plays a crucial role in the digestion and absorption of dietary fats. Cholylglycine is a primary bile acid, meaning it is synthesized directly in the liver and secreted into the gallbladder. From there, it is released into the small intestine during the digestion process.
The main function of cholylglycine is to emulsify dietary fats, aiding in their breakdown and absorption in the intestines. It accomplishes this by acting as a detergent-like substance that aids in the solubilization of fats, thus increasing their surface area and facilitating the action of digestive enzymes. Cholylglycine also helps in the absorption of fat-soluble vitamins, such as vitamin A, D, E, and K.
In addition to its role in digestion, cholylglycine also serves as a precursor for the production of secondary bile acids in the colon. These secondary bile acids can have important regulatory functions in various physiological processes, including modulating gut microbial composition and activity.
Cholylglycine measurements can be used to assess liver function, as abnormalities in its levels may indicate liver disease or dysfunction. Furthermore, cholylglycine can be used as a diagnostic marker for various gastrointestinal disorders, as its levels may be altered in conditions such as bile acid synthesis defects, liver cirrhosis, and gallstone formation.
Common Misspellings for CHOLYLGLYCINE
- xholylglycine
- vholylglycine
- fholylglycine
- dholylglycine
- cgolylglycine
- cbolylglycine
- cnolylglycine
- cjolylglycine
- cuolylglycine
- cyolylglycine
- chilylglycine
- chklylglycine
- chllylglycine
- chplylglycine
- ch0lylglycine
- ch9lylglycine
- chokylglycine
- chopylglycine
- chooylglycine
- choltlglycine
Etymology of CHOLYLGLYCINE
The word "cholylglycine" is derived from two main components: "cholyl" and "glycine".
1. Cholyl: This component originates from "cholic acid", which is a bile acid found in the liver of humans and animals. The term "cholic" comes from the Greek word "cholē", meaning "bile".
2. Glycine: This component is derived from the amino acid "glycine", which is one of the building blocks of proteins. The word "glycine" comes from the Greek word "glykys", meaning "sweet" or "sugar", referring to its sweet taste.
Combining these components, the term "cholylglycine" refers to a conjugate of cholic acid with glycine, often used as a marker for liver function tests.
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