How Do You Spell CHLOROMA?

Pronunciation: [klˈɔːɹə͡ʊmə] (IPA)

Chloroma is a medical term used to describe a mass that primarily contains myeloid cells. It is pronounced /klɔːˈrəʊmə/ according to the International Phonetic Alphabet (IPA). The word is derived from two Greek words, "chloros," meaning green, and "oma," meaning tumor. This refers to the green hue typically seen in the affected tissue. The spelling of the word is fairly straightforward, with the exception of the "h" after the "c" in the first syllable, which is silent.

CHLOROMA Meaning and Definition

1. Chloroma, also known as granulocytic sarcoma or myeloid sarcoma, is a rare solid tumor composed of immature white blood cells, specifically myeloid cells, that forms in extramedullary sites. This term is primarily used in the context of myelogenous leukemia and other myeloproliferative disorders.

   Chloroma tumors typically appear as single or multiple greenish masses due to high levels of myeloperoxidase enzyme within the cells, which gives them a characteristic green color upon exposure to air. These tumors can arise in various locations throughout the body, including the bones, skin, soft tissue, lymph nodes, and central nervous system.

   Chloroma usually occurs as an extramedullary manifestation of acute myeloid leukemia (AML) or other myeloproliferative neoplasms. It can be the initial presentation of leukemia or can develop concurrently with leukemia or during periods of remission. The presence of chloroma is often associated with a worse prognosis, increased risk of relapse, and a higher incidence of central nervous system involvement.

   Treatment of chloroma depends on the underlying hematologic disease and the specific location and extent of the tumor. It typically involves systemic chemotherapy, targeted therapies, and in some cases, radiation therapy or surgery. Chloromas can be challenging to manage due to their resistance to treatment and propensity for rapid growth.

   In summary, chloroma refers to a rare solid tumor composed of immature myeloid cells that often develops in extramedullary sites as a manifestation of myelogenous leukemia or other myeloproliferative disorders.

2. A condition marked by the occurrence of multiple growths, often of a greenish or greenish yellow color, on the periosteum of the bones of the face or skull and occasionally on the vertebrae, associated with the presence in the blood of numbers of lymphocytes or myeloblasts; green cancer, chlorosarcoma.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for CHLOROMA

• xhloroma
• vhloroma
• fhloroma
• dhloroma
• cgloroma
• cbloroma
• cnloroma
• cjloroma
• culoroma
• cyloroma
• chkoroma
• chporoma
• chooroma
• chliroma
• chlkroma
• chllroma
• chlproma
• chl0roma
• chl9roma
• chloeoma

Etymology of CHLOROMA

The word "chloroma" is derived from the Greek terms "chloros" meaning green and "oma" meaning tumor. The term was coined to describe a rare type of tumor that typically appears green due to the high content of myeloperoxidase, an enzyme found in certain types of leukemic cells.