How Do You Spell CHALONE?

Pronunciation: [t͡ʃˈalə͡ʊn] (IPA)

The spelling of the word "chalone" may be confusing for some due to its unusual combination of letters. However, its pronunciation can be easily explained using the International Phonetic Alphabet (IPA). The correct pronunciation is /kælɔːn/ with the stress on the first syllable. The "ch" is pronounced as the sound /k/ and the "a" is pronounced as the short sound /æ/. The "lone" portion is pronounced as /lɔːn/. "Chalone" is a type of protein that helps regulate cell division and growth.

CHALONE Meaning and Definition

1. A chalone, in biological terms, refers to a group of naturally occurring proteins that regulate the growth and division of cells. These proteins act as negative regulators, meaning they inhibit cell division and proliferation, thereby promoting cell differentiation and limiting tissue growth. Chalones play a crucial role in maintaining the balance and integrity of various physiological processes and developmental stages in different organisms.

   Chalones exert their inhibitory effects by binding to specific receptors on the surface of target cells, triggering a signaling cascade that ultimately leads to the suppression of cell division. This process ensures that cells grow and differentiate in a controlled manner, preventing uncontrolled proliferation that could potentially result in the development of diseases such as cancer.

   The discovery of chalones has had significant implications in the field of biomedical research, as they provide insights into the mechanisms underlying cell regulation and tissue homeostasis. Scientists have identified various types of chalones, including those involved in the regulation of cell growth and development in specific organs or tissues. Understanding the functions and interactions of chalones has paved the way for potential therapeutic applications, such as developing drugs that target these proteins to modulate cell division and promote tissue repair or regeneration.

   In conclusion, chalones are naturally occurring proteins that act as negative regulators of cell division, promoting cell differentiation and limiting tissue growth. Their discovery has significant implications in understanding cell regulation and has the potential for therapeutic applications in the future.

2. 1. Antihormone, an antagonistic hormone, one which opposes the action of another hormone. 2. An endocrine substance which inhibits or diminishes the activity of the cells of the body.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for CHALONE

• xhalone
• vhalone
• fhalone
• dhalone
• cgalone
• cnalone
• cjalone
• cualone
• chzlone
• chqlone
• chakone
• chapone
• chaoone
• chalkne
• challne
• chalpne
• chal0ne
• chal9ne
• chalobe
• chaloje

Etymology of CHALONE

The word "chalone" has a rather complex etymology with various linguistic influences. The term originates from the ancient Greek word "khalōn", meaning "implement" or "implement holder". This Greek word, in turn, derives from the verb "khalō", meaning "to let down" or "to loosen".

In the 20th century, the term was adopted and introduced into English by two different scientific fields, each with its own etymological origins:

1. Geology: In geology, a "chalone" refers to a self-propagating mineral formation, particularly a mineral deposit that forms between layers of rocks. Its usage in geology originated from French, where it was known as "chalonnage", meaning "a channeling" or "a deposit". This French term derived from "chalone" referring to a layer of ore embedded in rocky material.

2.

Plural form of CHALONE is CHALONES