Pronunciation: [sˈɛvɐdˌiːn] (IPA) 
Cevadine is spelled with the letters C-E-V-A-D-I-N-E. Its pronunciation can be written in IPA phonetic transcription as /sɛvədiːn/. The first syllable has a short "e" sound, followed by a "v" and a short "a". The second syllable has a long "e" sound, while the final syllable ends with a short "i" and a long "n". Cevadine is a chemical compound used in medicine as an antiseptic and disinfectant.
Cevadine is a noun that refers to a synthetic derivative of isonicotinic acid, primarily used in medicine as an antitubercular agent. It belongs to the class of antimycobacterial drugs known as nicotinic acid hydrazides and exhibits bacteriostatic properties against the tubercle bacilli.
As an antitubercular drug, cevadine inhibits the growth and replication of Mycobacterium tuberculosis, the bacterium responsible for causing tuberculosis. By targeting the bacterium's DNA metabolism, cevadine disrupts the synthesis of essential components required for the bacteria to grow and multiply. This mechanism of action effectively curtails the progression of the disease and assists in the eradication of the infection.
Cevadine is often used in combination therapy, where it is administered alongside other antitubercular drugs to maximize its effectiveness and minimize the emergence of drug resistance. It is typically given orally, allowing for convenient and easy administration to patients.
In addition to its antitubercular activity, cevadine has also shown potential antileishmanial properties, making it potentially useful in the treatment of leishmaniasis, a parasitic disease caused by the Leishmania species.
Cevadine, though effective, may exhibit certain side effects such as gastrointestinal disturbances, skin rashes, and hepatic toxicity. Therefore, its use requires careful monitoring and consideration of the patient's overall health condition.
An alkaloid occurring in cevadilla or sabadilla seeds, resembling in its properties veratrine.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
