Cerebral tabes is a medical condition characterized by progressive degeneration of the nerves, leading to sensory abnormalities such as pain and impairment of coordination. Its pronunciation in IPA phonetic transcription is səˈribrəl ˈteɪbiz, with the stress on the second syllable. The word cerebral is pronounced səˈribrəl, while tabes is pronounced ˈteɪbiz. The correct spelling of this term is crucial for proper diagnosis and treatment of patients suffering from this condition. Healthcare professionals must be well versed in the spelling and pronunciation of medical terms to ensure accurate communication with colleagues and patients.
Cerebral tabes, also known as general paresis of the insane (GPI), is a neurosyphilis condition characterized by progressive deterioration of the brain and central nervous system functions. It is a late-stage neurological complication resulting from untreated or inadequately treated syphilis infection.
Cerebral tabes manifests as a degenerative condition that primarily affects the cerebral cortex, the outer layer of the brain responsible for higher cognitive functions. It often begins with cognitive impairment, including memory loss, confusion, and personality changes. As the disease progresses, individuals may experience difficulties with language, concentration, and problem-solving abilities. In advanced stages, cerebral tabes may lead to severe psychiatric symptoms such as psychosis, mood disturbances, and inappropriate behavior.
The underlying cause of cerebral tabes is the spirochete bacterium Treponema pallidum, which is responsible for syphilis infection. If syphilis is left untreated or inadequately treated, the bacterium may invade the brain and central nervous system, causing the characteristic symptoms and pathological changes associated with cerebral tabes.
Diagnosis of cerebral tabes typically involves a combination of physical examinations, clinical history assessment, neuropsychological assessments, and laboratory tests to detect the presence of syphilis antibodies in the blood or cerebrospinal fluid. Treatment usually involves administration of long-term antibiotic therapy, such as penicillin, to eliminate the infection.
Although advancements in antibiotic treatments have significantly reduced the occurrence of cerebral tabes in recent years, it remains a relevant clinical entity particularly in cases of untreated or neglected syphilis. Hence, prevention through safe sexual practices and early medical intervention is crucial in avoiding the development of cerebral tabes.
A form of t. dorsalis in which the earliest symptoms are in the region innervated by the cranial nerves.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The term "cerebral tabes" is derived from two different sources: "cerebral" and "tabes".
1. Cerebral: The word "cerebral" is of Latin origin, stemming from the Latin word "cerebrum" which means "brain". It is related to the Greek word "keras" which means "head". Over time, "cerebrum" evolved into "cerebral" in modern English. In medical terminology, "cerebral" refers to anything related to the brain or the cerebrum.
2. Tabes: The term "tabes" comes from the Latin word "tabes" which means "wasting away" or "decay". It is related to the Latin verb "tabesco" which translates to "to waste away".