Cefalotin, also known as cephazolin, is a broad-spectrum antibiotic medication that belongs to the class of drugs known as cephalosporins. It is commonly used to treat bacterial infections caused by susceptible organisms. Cefalotin is primarily effective against Gram-positive bacteria, but it also demonstrates some activity against certain Gram-negative microorganisms.
Cefalotin works by inhibiting bacterial cell wall synthesis, thereby preventing the growth and reproduction of bacteria. It achieves this by binding to penicillin-binding proteins (PBPs) in the bacterial cytoplasmic membrane, which leads to the disruption of the cell wall formation process. Due to its mechanism of action, Cefalotin is considered a bactericidal agent, meaning it directly kills the bacteria rather than just inhibiting their growth.
This antibiotic is commonly utilized in the treatment of a variety of bacterial infections, including skin and soft tissue infections, respiratory tract infections, urinary tract infections, bone and joint infections, and certain types of postoperative infections. It is usually administered intravenously or intramuscularly, depending on the severity and location of the infection.
As with any antibiotic, Cefalotin is not effective against viral infections, such as the common cold or flu. It is also important for healthcare professionals to be aware of potential adverse effects and drug interactions associated with its use, and patients should take the medication exactly as prescribed to ensure optimal efficacy and minimize the risk of developing antibiotic resistance.
