How Do You Spell CEBPA?

Pronunciation: [sˈɛbpə] (IPA)

The spelling of the word "cebpa" can be explained using the International Phonetic Alphabet (IPA). In this transcription system, "c" is pronounced as /s/, "e" is pronounced as /ɛ/, "b" is pronounced as /b/, and "p" is pronounced as /p/. The final "a" is pronounced as /ə/. Thus, the correct pronunciation of "cebpa" is /sɛbpa/, with the stress on the first syllable. This word refers to a gene that is responsible for encoding a protein important in the development of blood cells.

CEBPA Meaning and Definition

1. C/EBPα, also known as CEBPA, is an abbreviation for CCAAT/enhancer-binding protein alpha. It is a transcription factor protein that plays a critical role in the regulation of gene expression. Transcription factors are proteins that bind to DNA and help initiate or repress the transcription of specific genes, which is the first step in gene expression.

   CEBPA is primarily involved in the regulation of genes related to cell growth, differentiation, and immune response. It is especially crucial in the development and differentiation of myeloid cells, which are a type of white blood cells involved in the immune response and blood clotting. During hematopoiesis (the process of blood cell formation), CEBPA is responsible for the transformation of hematopoietic stem cells into myeloid progenitor cells.

   Mutations or dysregulation of the CEBPA gene have been identified in various diseases, particularly in acute myeloid leukemia (AML). In AML, mutations in the CEBPA gene often disrupt its normal function, leading to abnormal differentiation and proliferation of immature blood cells.

   Overall, CEBPA is an essential transcription factor involved in the regulation of gene expression and the control of cell differentiation and growth. Understanding its function and the impact of its mutations is vital for gaining insights into various cellular processes and diseases, particularly those related to blood cell development and leukemogenesis.

Common Misspellings for CEBPA

• CeBPS
• cebpe
• vebpa
• debpa
• ceb-a
• ceb0a
• xcebpa
• cxebpa
• vcebpa
• cvebpa
• fcebpa
• cfebpa
• dcebpa
• cdebpa
• cwebpa
• cewbpa
• cedbpa
• c3ebpa
• ce3bpa
• cevbpa