How Do You Spell CASPASE?

Pronunciation: [kˈaspe͡ɪs] (IPA)

Caspases are a family of enzymes that play a crucial role in programmed cell death. The spelling of "caspase" comes from the term "cysteine caspase" and is pronounced /ˈkæs.peɪz/ in IPA phonetic transcription. The "c" represents the "k" sound, the "a" is pronounced as "æ", the "s" is pronounced as "s", the "p" is pronounced as "p", the "a" is pronounced as "æ" again, and the "se" is pronounced as "z". The correct spelling and pronunciation of "caspase" are important in the field of genetics and molecular biology.

CASPASE Meaning and Definition

1. Caspases are a family of enzymes that play a crucial role in apoptosis, which is a tightly regulated process of programmed cell death. The term "caspase" is derived from "cysteine-aspartic protease" because these enzymes cleave peptide bonds after aspartate residues using a cysteine residue as a nucleophile. In the human body, caspases are involved in various cellular functions such as cell differentiation, proliferation, and inflammation.

   There are two main types of caspases: the initiator caspases and the effector (executioner) caspases. The initiator caspases, including caspase-8 and caspase-9, are responsible for initiating apoptosis signals in response to specific cellular cues. These signals can be triggered by extracellular death ligands binding to receptors on the cell surface or by internal cellular stresses. Once activated, the initiator caspases cleave and activate the effector caspases, such as caspase-3 and caspase-7, which ultimately execute the destruction of the cell by cleaving vital cellular components.

   Caspases play a crucial role in maintaining tissue homeostasis, removing damaged or infected cells, and preventing the proliferation of abnormal cells. Dysregulation of caspase activity has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Consequently, caspases have become important therapeutic targets for drug development to modulate cell death in order to treat these diseases.

Common Misspellings for CASPASE

• xaspase
• vaspase
• faspase
• daspase
• czspase
• csspase
• cwspase
• cqspase
• caapase
• cazpase
• caxpase
• cadpase
• caepase
• cawpase
• casoase
• caslase
• cas-ase
• cas0ase
• caspzse
• caspasa

Etymology of CASPASE

The word "caspase" derives from the terms "cysteine-aspartic protease". The name combines the amino acid cysteine and aspartic acid, which form the active site of these protease enzymes. Caspases are involved in programmed cell death, or apoptosis, and play crucial roles in various biological processes.

Similar spelling word for CASPASE

• casebook.

Plural form of CASPASE is CASPASES