CARDENOLIDES Meaning and
Definition
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Cardenolides are a class of organic compounds that belong to the group of steroid glycosides. They are naturally occurring substances found mainly in plants, particularly in the Apocynaceae and Asclepiadaceae families. Cardenolides have a distinctive structure consisting of a steroid nucleus linked to a lactone ring. The lactone ring often contains five or six-membered carbon atoms.
These compounds have been studied for their significant biological activities, including cardiotonic, anti-inflammatory, and anticancer properties. Cardenolides are known to exhibit potent effects on the cardiovascular system, enhancing the contractile force of the heart muscle by inhibiting the action of the sodium-potassium ATPase pump. This mechanism increases the concentration of intracellular calcium ions, leading to enhanced myocardial contraction.
Some cardenolide derivatives, such as digoxin and digitoxin, have been widely used in the treatment of heart failure and certain arrhythmias. Additionally, cardenolides have shown promising anticancer effects, as they possess the ability to induce cell death in tumor cells while having minimal impact on normal cells.
Due to their diverse pharmacological activities, cardenolides have attracted considerable attention from scientists and researchers in the fields of medicine and natural product chemistry. Their unique chemical structures and potential therapeutic applications make them a significant area of interest for further investigation and drug development.
Common Misspellings for CARDENOLIDES
- cardanolides
- Cardinolides
- xardenolides
- vardenolides
- fardenolides
- dardenolides
- czrdenolides
- csrdenolides
- cwrdenolides
- cqrdenolides
- caedenolides
- caddenolides
- cafdenolides
- catdenolides
- ca5denolides
- ca4denolides
- carsenolides
- carxenolides
- carcenolides
- carfenolides
Etymology of CARDENOLIDES
The word "Cardenolides" originates from two main sources - "Cardenol" and "ide".
The term "Cardenol" is derived from the scientific name for the genus oleander, Nerium oleander, commonly known as the oleander plant. It was first isolated and identified from the oleander plant in the 19th century. The name "Cardenol" is a combination of "cardio" (meaning heart) and "oleander". This reflects the cardiac glycoside properties of the compounds found in the plant, as they have significant effects on the heart.
The suffix "ide" is commonly added to the end of chemical compounds to indicate a class or group of related substances. In the case of "Cardenolides", the suffix "ide" signifies that it is a class of compounds related to "Cardenol".
Similar spelling words for CARDENOLIDES
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