How Do You Spell CANRENONE?

Pronunciation: [kˈanɹɪnˌɒn] (IPA)

The word "Canrenone" is spelled phonetically as /kænˈrɛnoʊn/. IPA transcription breaks down the pronunciation of this word into its individual phonemes, with each symbol representing a specific sound. The "c" is pronounced as a "k" as in "cat," while the "a" is pronounced as "æ" like in "hat." The "n" is pronounced as "n" as in "never," and "o" is pronounced as "ɛ" as in "bed." Lastly, "ne" is pronounced as "noʊn" like in "own." Therefore, the spelling of "Canrenone" matches its phonetic pronunciation accurately.

CANRENONE Meaning and Definition

1. Canrenone is a pharmaceutical substance that serves as a potassium-sparing diuretic, meaning it promotes the elimination of excess water and sodium from the body while conserving potassium. It is also recognized as a mineralocorticoid receptor antagonist due to its ability to competitively bind with mineralocorticoid receptors and block the hormone aldosterone. Canrenone exerts its effects by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubule and collecting duct of the kidneys.

   This compound is chemically classified as a spironolactone metabolite, as it is formed during the metabolic breakdown of spironolactone, a well-known diuretic and mineralocorticoid receptor antagonist. Canrenone is primarily used in the management of various conditions where fluid retention is a concern, such as congestive heart failure, cirrhosis of the liver, and nephrotic syndrome.

   Due to its structural similarities to spironolactone, canrenone exhibits anti-androgenic properties and can also act as an androgen receptor antagonist. This feature has led to its use in treating certain dermatological conditions associated with excess androgens, including acne and hirsutism.

   However, it is important to note that canrenone should be used under medical supervision, and its usage may be associated with certain side effects, such as hyperkalemia (elevated potassium levels), gynecomastia (breast tissue enlargement in males), menstrual irregularities, and digestive disturbances.

Common Misspellings for CANRENONE

• Canreoone

Etymology of CANRENONE

The word "Canrenone" is derived from the chemical compound's systematic name, which is 17-Hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone. The name "Canrenone" is a portmanteau of "can" and "renone".

The term "Can" refers to the chemical compound's origin from Canrenoic acid, which is a compound closely related to aldosterone. Canrenoic acid is a synthetic derivative of spironolactone, a medication that acts as an aldosterone antagonist. "Can" is likely taken from the name of Canrenoic acid to indicate the compound's relationship with aldosterone and spironolactone.

The term "Renone" is a suffix commonly used in chemistry to refer to a lactone derivative.

Similar spelling word for CANRENONE

• kynurenine.