CA ATPASE Meaning and
Definition
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Ca ATPase, also known as Calcium ATPase, is a membrane-bound enzyme that plays a crucial role in maintaining calcium homeostasis within cells. It belongs to the family of P-type ATPases, which are ATP-driven ion pumps that actively transport ions across cellular membranes.
Ca ATPase is primarily responsible for removing calcium ions from the cytoplasm into the intracellular compartments, such as the endoplasmic reticulum and mitochondria, or extracellular space. This transport process is essential to regulate the concentration of calcium ions, a critical intracellular messenger, and to restore low calcium levels after cellular signaling events.
The enzyme utilizes the energy derived from the hydrolysis of adenosine triphosphate (ATP) to actively pump calcium ions against their concentration gradient. It functions by undergoing a series of conformational changes in response to ATP binding, hydrolysis, and phosphate release, facilitating calcium ion transport across the membrane.
The activity of Ca ATPase is regulated by various factors, including the concentration of calcium ions, membrane potential, and phosphorylation state. Different isoforms of Ca ATPase are found in various tissues and organelles, each displaying unique kinetic properties and tissue-specific functions.
Dysfunction of Ca ATPase can have severe consequences on cellular calcium homeostasis, leading to numerous pathological conditions such as muscle disorders, cardiovascular diseases, and neurodegenerative disorders. Consequently, this enzyme represents a vital target for the development of therapeutic interventions to restore calcium balance in diseased states.
Common Misspellings for CA ATPASE
- xa atpase
- va atpase
- fa atpase
- da atpase
- cz atpase
- cs atpase
- cw atpase
- cq atpase
- ca ztpase
- ca stpase
- ca wtpase
- ca qtpase
- ca arpase
- ca afpase
- ca agpase
- ca aypase
- ca a6pase
- ca a5pase
- ca atoase
- ca atlase
Etymology of CA ATPASE
The word "Ca ATPase" is a shortened form of "Calcium ATPase".
The etymology of "calcium" can be traced back to the Latin word "calx", which means lime or limestone. It refers to the element calcium, which plays a vital role in many biological processes.
"ATPase" is a combination of "adenosine triphosphate" (ATP) and "ase". ATP is a high-energy molecule that acts as a fuel source in cellular activities, while the suffix "ase" signifies an enzyme or a protein that catalyzes a specific biochemical reaction. Hence, "ATPase" refers to an enzyme that hydrolyzes ATP, releasing energy.
By combining these two terms, "Ca ATPase" indicates an enzyme that is specific to calcium ions, facilitating the transport of calcium across cellular membranes using the energy provided by ATP.
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