"Brunners Glands" is a term used to refer to the gastric glands that produce mucus in the duodenum of the digestive system. The correct spelling of this term is pronounced as "ˈbʁʊnɐz ɡlants" in IPA phonetic transcription. The initial "B" is pronounced as a voiced bilabial stop, followed by a vowel sound similar to "uh". The "n" is a nasal sound, and the "z" is a voiced sibilant. The term "glands" is pronounced as "ɡlants", with a hard "g" sound and an "l" sound followed by a short "a".
Brunner's glands, also known as duodenal glands, are specialized mucous glands located in the submucosa layer of the duodenum, which is the first part of the small intestine. These glands are named after the Swiss anatomist Johann Conrad Brunner, who first described them in the 18th century.
The primary function of Brunner's glands is to secrete mucus, a slippery substance that helps in lubrication and protection of the duodenal lining. The mucus produced by these glands serves multiple purposes. It provides a protective layer to prevent damage to the duodenal epithelial cells caused by the acidic chyme (partially-digested food) coming from the stomach. Additionally, it neutralizes the acidity of the chyme, creating an optimal pH environment for enzyme activity in the small intestine.
The secretion of Brunner's glands is under the control of various factors, including hormonal signals. Secretin, a hormone released by the intestinal walls in response to acidic chyme, stimulates the production and release of mucus from these glands. Consequently, the increased mucus secretion aids in buffering the acidity and maintaining the pH balance in the duodenum.
Pathological conditions that can affect Brunner's glands include duodenal ulcers and duodenitis. Inflammation or damage to these glands can disrupt their mucus production, potentially impairing the protective mechanisms of the duodenal lining and leading to complications.
In summary, Brunner's glands are specialized mucous glands located in the duodenum that secrete mucus to protect the lining of the small intestine and aid in the digestion process.
The term "Brunners glands" is named after the Swiss anatomist, Johann Conrad Brunner, who first described these glands in 1681. Brunner's glands are a type of duodenal glands found in the submucosa of the duodenum, the first part of the small intestine. They secrete a mucus-rich fluid that helps neutralize the acidic chyme (partially digested food) coming from the stomach, protecting the lining of the small intestine.