How Do You Spell BROXURIDINE?

Pronunciation: [bɹˈɒksjʊɹˌɪdiːn] (IPA)

Broxuridine is a chemotherapy drug that is used to treat cancer. This word consists of four syllables: brok-su-ri-deen. The first syllable, "brok," is pronounced with a short o sound like in "rock." The second syllable, "su," is pronounced with a short u sound like in "sun." The third syllable, "ri," is pronounced with a long e sound like in "be." The fourth syllable, "deen," is pronounced with a long e sound like in "teen." The IPA transcription for this word is /ˌbrɑkˈsjʊrɪdiːn/.

BROXURIDINE Meaning and Definition

1. Broxuridine, also known as 5-bromo-2'-deoxyuridine (BrdU), is a synthetic nucleoside analog of thymidine, a constituent of DNA. It is frequently used as a research tool in molecular biology and cellular biology, particularly in the field of DNA replication and cell proliferation studies.

   As a nucleoside analog, broxuridine is structurally similar to thymidine, but with a bromine atom substitution at the 5 position. This modification allows for easy detection and tracking of the incorporated broxuridine through immunohistochemical or immunocytochemical methods using specific antibodies. This feature has made broxuridine popular for studying cell division and the synthesis of new DNA strands.

   When added to cell culture or administered to an organism, broxuridine is enzymatically converted into its active form, BrdUTP. BrdUTP can be incorporated into the growing DNA chains in place of thymidine during cell replication, causing the newly synthesized DNA to be labeled with this modified nucleoside. By combining specific antibodies that can recognize BrdU with various visualization techniques, researchers can examine and quantify the level of cell proliferation, differentiation, and DNA synthesis.

   Broxuridine has proven to be a valuable tool in studying various biological processes, including cell cycle regulation, tumor growth, tissue regeneration, and neuronal development. Additionally, it has been widely used in cancer research to investigate the effects of anti-cancer drugs on cell proliferation.

   Overall, broxuridine serves as an essential compound in molecular and cellular biology, enabling scientists to gain insights into fundamental biological mechanisms and providing a basis for understanding numerous diseases and potential therapeutic approaches.

Common Misspellings for BROXURIDINE

• vroxuridine
• nroxuridine
• hroxuridine
• groxuridine
• beoxuridine
• bdoxuridine
• bfoxuridine
• btoxuridine
• b5oxuridine
• b4oxuridine
• brixuridine
• brkxuridine
• brlxuridine
• brpxuridine
• br0xuridine
• br9xuridine
• brozuridine
• brocuridine
• broduridine
• brosuridine

Etymology of BROXURIDINE

The word "Broxuridine" is a combination of "Brox" and "uridine".

"Brox" stands for Bromodeoxyuridine, which is a compound derived from Uracil, a nucleotide base found in RNA. "Bromo" refers to the bromine atom that is added to the structure of Uracil. Bromodeoxyuridine is often used as a research tool to study DNA synthesis and cell proliferation.

"Uridine" is a nucleoside, which is a combination of the nucleobase Uracil and the sugar ribose. It is a component of RNA and plays a role in various cellular processes.

Therefore, "Broxuridine" is a compound name created by combining the two words to represent the specific compound that is derived from Uracil called Bromodeoxyuridine.