How Do You Spell BRDU?

Pronunciation: [bˌiːˌɑːdˈiː jˈuː] (IPA)

The term BrdU is often used in biology to refer to 5-bromo-2'-deoxyuridine, a nucleoside analog that is incorporated into DNA during cell replication. Its spelling can be explained using the International Phonetic Alphabet (IPA) notation as follows: the "B" is pronounced as the voiced bilabial stop /b/, followed by the "r" sound represented by the alveolar approximant /ɹ/. The "d" sound is pronounced as the voiced alveolar stop /d/, while the "U" is represented by the high back rounded vowel /u/.

BRDU Meaning and Definition

1. BrdU (Bromodeoxyuridine) is a chemical compound commonly used as a molecular marker in the field of biology and medicine. It is a synthetic analog of the nucleotide thymidine, wherein a bromine atom has been substituted for the hydrogen atom at the 5th carbon position of the uracil ring. This characteristic chemical modification allows scientists to detect and track the incorporation of BrdU into newly synthesized DNA.

   When added to cultured cells or injected into living organisms, BrdU is selectively incorporated into the DNA of dividing cells during the S phase of the cell cycle. As a result, it serves as a valuable tool for studying cell proliferation, DNA synthesis, and cell dynamics. Additionally, BrdU can be visualized using immunohistochemical techniques, making it useful for identifying and quantifying actively dividing cells in tissues or organs.

   In research, BrdU has wide-ranging applications, such as studying cancer biology, neurogenesis, tissue repair, and regenerative medicine. It aids in determining the rate of cell division, assessing the effects of various stimuli or treatments on cell proliferation, and investigating the origins and kinetics of different cell populations.

   Overall, BrdU plays a significant role as a molecular marker, allowing scientists to elucidate fundamental biological processes and gain insights into complex cellular activities. Its versatility and reliability have made it an indispensable tool in many scientific investigations.

Common Misspellings for BRDU

• prdu
• bddu
• brdyo
• brtyu

Etymology of BRDU

The word "BrdU" is an abbreviation for "bromodeoxyuridine". The etymology of "bromodeoxyuridine" is as follows:

- Bromo: Derived from the Greek word "bromos", meaning "stench" or "bad odor", referring to the odor of bromine.

- Deoxy: A prefix meaning "without oxygen" or "lacking oxygen".

- Uridine: Derived from "uracil" and "ribose", which are the constituents of the compound.

Therefore, "bromodeoxyuridine" is a compound name that signifies a derivative of uridine with a bromine substitution on the deoxyribose sugar component. The shorthand "BrdU" is commonly used due to the length and complexity of the full name.