BONE RESORPTION Meaning and
Definition
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Bone resorption is a physiological process in which bone tissue is broken down and reabsorbed by specialized cells called osteoclasts, resulting in the release of minerals, such as calcium and phosphate, into the bloodstream. This process is an essential component of bone remodeling, which helps maintain the integrity and strength of the skeleton.
During bone resorption, osteoclasts attach to the bone surface and secrete enzymes that break down the mineralized bone matrix. These enzymes degrade collagen fibers, which provide structural support to the bone, and dissolve the hydroxyapatite crystals, which are responsible for the hardness of the bone. As a result, the bone tissue gets reabsorbed, allowing for the release of minerals into the bloodstream and the subsequent remodeling and renewal of the skeleton.
Bone resorption is tightly regulated by various hormones, including parathyroid hormone (PTH) and calcitonin, as well as cytokines and growth factors. It plays a crucial role in maintaining calcium homeostasis, repairing micro-damage in bones, and adapting bone structure to mechanical stress and hormonal changes.
However, excessive bone resorption can lead to various pathological conditions, such as osteoporosis, where bone density decreases, and the risk of fractures increases. Understanding the mechanisms underlying bone resorption is crucial for the development of therapies targeting bone diseases and for promoting skeletal health and integrity.
Common Misspellings for BONE RESORPTION
- vone resorption
- none resorption
- hone resorption
- gone resorption
- bine resorption
- bkne resorption
- blne resorption
- bpne resorption
- b0ne resorption
- b9ne resorption
- bobe resorption
- bome resorption
- boje resorption
- bohe resorption
- bonw resorption
- bons resorption
- bond resorption
- bonr resorption
- bon4 resorption
- bon3 resorption
Etymology of BONE RESORPTION
The word "resorption" dates back to the early 19th century and comes from the Latin word "resorptio", which means "a sucking in". It is derived from the verb "resorbere", meaning "to suck back or swallow up".
The word "bone" can be traced back to the Old English word "bān", which is also similar in other Germanic languages. It has Proto-Germanic origins and shares similarities with Old Norse "bein" and Old High German "bein".
Therefore, when combined, "bone resorption" refers to the process where bones are being sucked back or absorbed, leading to a loss or breakdown of bone tissue.
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