BMRB, abbreviated as the Biological Magnetic Resonance Bank, is a comprehensive database that serves as a repository for experimental data related to macromolecules and their nuclear magnetic resonance (NMR) spectroscopy. It is an essential resource for researchers and scientists to access and contribute to the field of structural biology.
In a wider sense, BMRB is an acronym for the BioMagResBank, which encompasses both the NMR-STAR data dictionary and a corresponding database that archives NMR spectral data and derived atomic coordinates for biological macromolecules. It primarily focuses on proteins, nucleic acids, and other biological macromolecules. The BMRB contains a vast collection of NMR data, including chemical shift assignments, coupling constants, relaxation parameters, and other related experimental measurements. These data provide valuable insights into the three-dimensional structure, dynamics, and interactions of biological macromolecules, aiding in the understanding of their functions and mechanisms.
The BioMagResBank operates under the guidance of the Protein Data Bank (PDB), and its mission is to collect, validate, archive, and distribute NMR experimental data and derived structural information openly and freely to the scientific community. The data stored in BMRB are highly valuable for researchers studying protein structure determination, functional analysis, and drug design.
In summary, the BMRB is a dedicated database and data dictionary that plays a crucial role in the dissemination and preservation of NMR-derived data, supporting research and discoveries in structural biology.
