The term "Blood Sedimentation" refers to a medical procedure that measures the rate at which red blood cells settle in a tube over time. The spelling of the term is phonetically transcribed as /blʌd sɛdəmɛnˈteɪʃən/, where the stress is on the second syllable. The word "sedimentation" comes from the Latin root "sede," meaning "to settle," and "mentation," meaning "the act of measuring." This procedure helps diagnose a variety of inflammatory conditions and infections by evaluating the rate of red blood cell clumping in the blood sample.
Blood sedimentation, also known as erythrocyte sedimentation rate (ESR), refers to a laboratory test used to measure the rate at which red blood cells (erythrocytes) settle to the bottom of a tube over a specified period of time. The test determines the presence and intensity of inflammation in the body, as elevated sedimentation rates are typically associated with various conditions that trigger inflammation, such as infections, autoimmune diseases, and certain types of cancers.
The process of blood sedimentation begins by collecting a blood sample, usually from a vein in the arm. The blood is then placed into a narrow, vertical, and calibrated tube, where it is allowed to stand undisturbed for a specific length of time, typically one hour. In this time, the red blood cells settle to the bottom of the tube due to their greater density compared to the plasma. The distance in millimeters that the red blood cells have settled within the tube during the set time period is measured and reported as the sedimentation rate.
Blood sedimentation is an indirect and non-specific indicator of inflammation, as it does not identify the exact cause or location of inflammation. Nonetheless, it serves as an important diagnostic tool when used in conjunction with other clinical information to monitor disease progression, assess response to treatment, and aid in the diagnosis of certain conditions. Although blood sedimentation is a widely used test, it is important to note that various factors, such as age, sex, anemia, medications, and pregnancy, can influence the results and should be taken into consideration when interpreting the findings.
The word "blood sedimentation" is derived from two separate terms: "blood" and "sedimentation".
- "Blood" originates from the Old English word "blōd", which can be traced back to the Proto-Germanic "blōþam" and the Proto-Indo-European root "bhlo-to", meaning "that which bursts out" or "to swell, gush, spurt". This ancient root denotes the vital fluid that circulates in all vertebrates, carrying oxygen, nutrients, and removing waste.
- "Sedimentation" comes from the Latin verb "sedimentum", which is derived from the noun "sedimentum" meaning "a settling" or "that which has settled". The Latin term originates from the verb "sedere" meaning "to sit", indicating the action of particles or substances settling down at the bottom of a liquid due to gravitational force.