Birnaviridae is a family of small, non-enveloped viruses that belong to the order of viruses known as Picornavirales. This family includes several species of double-stranded RNA (dsRNA) viruses that primarily infect animals, particularly birds and fish. The name "Birnaviridae" is derived from birna, an Old Norse term meaning "small bird."
Members of the Birnaviridae family can cause various diseases in their hosts, ranging from mild to severe. For example, Infectious bursal disease virus (IBDV) is a well-known member of this family that affects young chickens, causing a highly contagious disease called Infectious Bursal Disease (IBD) or Gumboro disease. It targets the immune system, specifically the bursa of Fabricius, leading to immunosuppression and increased susceptibility to secondary infections.
Birnaviruses typically have a non-segmented, linear genome composed of two segments (A and B) of dsRNA. Segment A usually encodes the viral capsid proteins, while segment B encodes the viral RNA-dependent RNA polymerase. These viruses have a characteristic isometric or spherical shape with a diameter of about 60-80 nanometers.
The transmission of Birnaviridae viruses can occur through direct contact with infected individuals, fecal-oral route, or contaminated water. Control and prevention strategies for Birnaviridae infections often involve vaccination, strict biosecurity measures, and proper disinfection practices. Research is ongoing to better understand the biology, epidemiology, and pathogenesis of these viruses in order to develop effective measures for their control and management.
The word "Birnaviridae" is derived from the combination of two parts: "birna" and "viridae".
The first part, "birna", refers to BIRNAVirus, which stands for Birna-like Virus. The name "Birna" was chosen because it was initially known to infect the Bursa of Fabricius in birds. The Bursa of Fabricius is an organ in birds important for the development of B-lymphocytes, which play a crucial role in the immune system.
The second part, "viridae", is a suffix commonly used to denote a family classification in virology. It derives from the Latin word "viridae", meaning "green", which was originally used as a classification for green algae. This suffix is widely used in family names of viruses.