Correct spelling for the English word "bellones" is [bˈɛlə͡ʊnz], [bˈɛləʊnz], [b_ˈɛ_l_əʊ_n_z] (IPA phonetic alphabet).
Bellones is a term primarily used in the field of pathology and oncology. It refers to a specific type of immune cell known as natural killer cells or NK cells. NK cells are a subset of lymphocytes that play a crucial role in the immune system's defense against various diseases, including cancer.
Bellones are characterized by their ability to recognize and directly kill abnormal or infected cells without prior exposure or activation. Unlike other immune cells, bellones do not require the presence of specific antigens or major histocompatibility complex (MHC) molecules to initiate their cytotoxic activity.
The name "bellones" is derived from the phrase "belle inones" meaning "beautiful killers" in Italian, as these cells possess a remarkable potency to eliminate target cells. They execute their functions through the release of cytotoxic granules containing perforin and granzymes, which induce apoptosis or programmed cell death in the target cells. Additionally, bellones can also produce various cytokines and chemokines to enhance the immune response and recruit other immune cells to the site of infection or tumor.
The discovery and study of bellones have provided valuable insights into the field of immunotherapy, as they have the potential to be harnessed in the development of novel treatments for cancer and other diseases. Harnessing the power of bellones may enable the development of targeted therapies that boost the immune system's natural defenses, providing more effective and personalized treatments for patients.
Pedunculated tumors in the posterior nares of the horse; they sometimes fall back over the opening of the glottis, causing intermittent roaring.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.