How Do You Spell AZAGUANINE?

Pronunciation: [ˈazɐɡjˌuːɐnˌa͡ɪn] (IPA)

Azaguanine is a chemical compound that is often used in research laboratories. The correct spelling is [azəɡwəˈnin], which is represented in the International Phonetic Alphabet (IPA). The first syllable, "aza," is pronounced with a schwa sound followed by a short "a" sound as in "apple." The second syllable, "gua," is pronounced with a "gw" sound followed by a neutral vowel. The final syllable, "nine," is pronounced with a long "i" sound followed by a neutral vowel. With this knowledge, one can confidently pronounce and spell the word Azaguanine in any situation.

AZAGUANINE Meaning and Definition

1. Azaguanine is a pharmacological compound that belongs to the class of antimetabolites. It is a synthetic analog of the naturally occurring nucleobase guanine. Azaguanine is primarily used in the field of medical research and is commonly employed as a selective agent in molecular biology and genetics experiments.

   As an antimetabolite, azaguanine functions by interrupting the normal metabolic processes involving guanine in cells. It acts as a purine analog, which means it can substitute for guanine during DNA and RNA synthesis. However, azaguanine is structurally modified in a way that renders it toxic to cells, preventing them from efficiently utilizing guanine and thus inhibiting their ability to proliferate.

   In laboratory settings, azaguanine is commonly utilized in a process known as genetic selection or positive selection. It is added to culture media or growth plates in order to selectively eliminate cells that have not successfully incorporated a desired genetic modification or mutation. By allowing only the cells that have integrated the desired genetic material to survive and proliferate, azaguanine enables researchers to isolate and study specific genetic variants.

   Additionally, azaguanine has been used in scientific studies to better understand the mechanisms of how cells process and utilize guanine, elucidate pathways involved in DNA and RNA synthesis, and investigate the impact of guanine analogs on cellular function and metabolism.

Common Misspellings for AZAGUANINE

• azaguamine

Etymology of AZAGUANINE

The word "Azaguanine" is derived from two components: "Aza-" and "guanine".

1. "Aza-" is a prefix derived from the Greek word "azotos", meaning "nitrogen". In chemistry, the prefix "aza-" is used to indicate the addition of one nitrogen atom in a molecule that originally does not contain nitrogen.

2. "Guanine" is a nucleobase that is one of the four building blocks of DNA and RNA. It is represented by the letter "G" in the genetic code and is one of the purine bases.

Combining these two components, "Azaguanine" refers to a molecule that is derived from guanine by adding an additional nitrogen atom.

Similar spelling words for AZAGUANINE

• isoguanine,
• ascanian,
• asikainen,
• Esquinon,
• oskanyan,
• uosukainen.