How Do You Spell AXONAL TRANSPORT?

Pronunciation: [ˈaksɒnə͡l tɹˈanspɔːt] (IPA)

The spelling of the term "Axonal Transport" is fairly straightforward when broken down phonetically. The first syllable, "Ax", is pronounced with a short a sound, followed by the consonant cluster "x", which is pronounced as the letter "ks". The next syllable, "o", is pronounced with a short "uh" sound, and the final syllable "nal" is pronounced with a long "a" sound. "Transport" is spelled as it sounds, with the stress on the second syllable. In IPA, it is transcribed as /ˈæksənəl ˈtrænspɔːrt/.

AXONAL TRANSPORT Meaning and Definition

1. Axonal transport refers to the process of transportation of various substances in both directions along the length of the axon (the long extension of a nerve cell) within the nervous system. Axons are responsible for transmitting electrical signals or impulses from one neuron to another or to a target organ or tissue. However, they also require a continuous supply of essential molecules and organelles to maintain their structural integrity and perform their functions effectively.

   Axonal transport can be classified into two main forms: anterograde transport and retrograde transport. Anterograde transport involves the transport of materials from the cell body towards the axon terminals or synaptic sites. Conversely, retrograde transport is the movement of substances from the axon terminals towards the cell body. Both forms of axonal transport are vital for the proper functioning and survival of neurons.

   Various types of molecules and organelles are transported using axonal transport mechanisms, including neurotransmitters, proteins, lipids, ions, mitochondria, and even pathogens such as viruses. These substances are transported within the axon by molecular motors called kinesins and dyneins, which utilize the energy generated from ATP hydrolysis to "walk" along the microtubules present in the axon.

   Axonal transport plays a significant role in various physiological processes, such as synaptic transmission, axonal growth, maintenance of cellular homeostasis, and the removal of cellular waste. Disruptions in axonal transport have been implicated in the pathogenesis of numerous neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Understanding the intricacies of axonal transport is essential for advancing our knowledge of neuronal function and developing potential therapeutic interventions for neurological disorders.

Common Misspellings for AXONAL TRANSPORT

• zxonal transport
• sxonal transport
• wxonal transport
• qxonal transport
• azonal transport
• aconal transport
• adonal transport
• asonal transport
• axinal transport
• axknal transport
• axlnal transport
• axpnal transport
• ax0nal transport
• ax9nal transport
• axobal transport
• axomal transport
• axojal transport
• axohal transport
• axonzl transport
• axonsl transport

Etymology of AXONAL TRANSPORT

The etymology of the word "Axonal Transport" is as follows:

1. Axon: The term "axon" comes from the Greek word "axōn", which means "axis" or "axis of a wheel". It was first used in the context of biology by German anatomist Heinrich Wilhelm Waldeyer in 1891 to refer to the long, slender projection of a nerve cell that transmits electrical impulses away from the cell body.

2. Transport: The word "transport" comes from the Latin word "transportare", which is a combination of "trans" meaning "across" or "beyond", and "portare" meaning "to carry". In English, the word "transport" refers to the act of carrying or moving something from one place to another.

Plural form of AXONAL TRANSPORT is AXONAL TRANSPORTS