AUTOPHAGOCYTOSES Meaning and
Definition
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Autophagocytosis refers to the process by which a cell engulfs and degrades its own intracellular components in order to recycle and maintain cellular homeostasis. It is a critical mechanism for cellular quality control, allowing the cell to remove damaged or unnecessary organelles, proteins, and macromolecules.
The term autophagocytosis combines two fundamental processes: autophagy and phagocytosis. Autophagy, derived from the Greek words "auto" (self) and "phagy" (eating), is the cellular process involved in the sequestration and transport of cytoplasmic cargo to the lysosomes for degradation and recycling. Phagocytosis, on the other hand, refers to the cellular process by which cells engulf and internalize solid particles, such as bacteria, foreign bodies, or cellular debris.
During autophagocytosis, a specialized membrane structure called the autophagosome forms around the target cytoplasmic components. This double-membrane vesicle then fuses with the lysosome, generating an autolysosome. Within the autolysosome, the trapped components are degraded by the hydrolytic enzymes present in the lysosome, including proteases, nucleases, and lipases. The resulting breakdown products are then released back into the cytoplasm for reuse in cellular processes, such as energy production or building new cellular components.
Autophagocytosis is a tightly regulated process that plays a crucial role in various physiological and pathological conditions, including development, aging, immunity, and disease. Dysregulation of autophagocytosis has been associated with various disorders, such as neurodegenerative diseases, cancer, and metabolic disorders. Understanding the cellular and molecular mechanisms underlying
Common Misspellings for AUTOPHAGOCYTOSES
- zutophagocytoses
- sutophagocytoses
- wutophagocytoses
- qutophagocytoses
- aytophagocytoses
- ahtophagocytoses
- ajtophagocytoses
- aitophagocytoses
- a8tophagocytoses
- a7tophagocytoses
- aurophagocytoses
- aufophagocytoses
- augophagocytoses
- auyophagocytoses
- au6ophagocytoses
- au5ophagocytoses
- autiphagocytoses
- autkphagocytoses
- autlphagocytoses
- autpphagocytoses
Etymology of AUTOPHAGOCYTOSES
The word "autophagocytosis" is derived from three main components: "auto-", "phago-", and "cytosis".
1. "Auto-" is a prefix that comes from the Greek word "autós" meaning "self". In scientific terminology, it often denotes self-regulation or self-digestion.
2. "Phago-" is another Greek prefix that stems from the verb "phagéin", meaning "to eat" or "to devour". It is commonly used to indicate ingestion or engulfment.
3. "Cytosis" is derived from the Greek word "kútos", which signifies a "cell". It is frequently associated with the process or action happening within or involving cells.
Combining these components, "autophagocytosis" refers to the process by which a cell engulfs or internalizes its own components (organelles, proteins, etc.
Similar spelling word for AUTOPHAGOCYTOSES
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