AUERS BODIES Meaning and
Definition
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Auers bodies, also known as Auer rods, are abnormal structures that are found within the cytoplasm of certain cells, predominantly seen in leukemic blast cells or other malignant cells associated with acute myeloid leukemia (AML). These rod-shaped structures typically contain crystalline inclusions that are composed of fused azurophilic granules. Auers bodies are considered a pathological feature and can be identified through microscopic examination.
The presence of Auers bodies in cells is considered a diagnostic characteristic of AML, allowing for differentiation from other types of leukemias or myelodysplastic syndromes. However, it is important to note that Auers bodies are not present in all cases of AML and may also be observed in other myeloproliferative disorders.
The formation of Auers bodies is believed to be associated with an abnormal maturation process of myeloid cells, resulting in the accumulation of granular material. This abnormality is thought to interfere with the normal cellular processes and contribute to the development and progression of AML.
The identification and examination of Auers bodies play a significant role in the diagnosis, classification, and monitoring of AML patients. By observing the presence or absence, as well as the abundance of these structures, healthcare professionals can gain insights into the prognosis and response to treatment for individuals with AML.
In conclusion, Auers bodies are abnormal rod-shaped structures found in certain cells, particularly leukemic blast cells, and are characteristic of acute myeloid leukemia.
Etymology of AUERS BODIES
The term Auers bodies is named after the German pathologist, Alfred Auersperg. They are eosinophilic cytoplasmic inclusions found in certain types of leukemia and lymphoma cells. As the discoverer of these structures, Alfred Auersperg's name became associated with them, giving rise to the term Auers bodies.
