The word "atrio" is spelled as /ˈæt.ri.oʊ/. The first syllable is pronounced with the short "a" sound as in "cat," followed by the "t" and "r" sounds. The second syllable is pronounced with a long "e" sound as in "see," and ends with the "o" sound. The combination of letters "io" is commonly used in medical terminology to denote a part of the body, such as atrioventricular (AV) node or atrioventricular (AV) block.