ATPASE H Meaning and
Definition
-
ATPase H is an enzyme that belongs to the family of ATPases, which are enzymes that catalyze the hydrolysis of adenosine triphosphate (ATP) to adenosine diphosphate (ADP) and inorganic phosphate (Pi). More specifically, ATPase H is a subunit of the vacuolar ATPase (V-ATPase), a highly conserved protein complex found in eukaryotic cells.
The V-ATPase is responsible for acidifying intracellular compartments such as lysosomes, endosomes, and secretory vesicles. This acidification is vital for various cellular processes, including protein degradation, receptor-mediated endocytosis, and neurotransmitter uptake. It also assists in regulating the pH of certain extracellular environments.
ATPase H plays a crucial role in the assembly and function of the V-ATPase complex. It is responsible for the ATP hydrolysis activity necessary for proton pumping across the intracellular membranes. By utilizing the energy derived from ATP hydrolysis, ATPase H helps maintain the acidic environment within the organelles, which is essential for their proper functioning.
Mutations in ATPase H or dysfunction of the V-ATPase have been associated with various diseases, including osteoporosis, renal tubular acidosis, and certain neurological disorders. Understanding the function and regulation of ATPase H is therefore of great importance in elucidating the underlying mechanisms of these diseases and in the development of potential therapeutic interventions.
Common Misspellings for ATPASE H
- ztpase h
- stpase h
- wtpase h
- qtpase h
- arpase h
- afpase h
- agpase h
- aypase h
- a6pase h
- a5pase h
- atoase h
- atlase h
- at-ase h
- at0ase h
- atpzse h
- atpsse h
- atpwse h
- atpqse h
- atpaae h
- atpaze h
Infographic
Add the infographic to your website:
