AT HOOK MOTIF Meaning and
Definition
-
The AT hook motif is a DNA-binding motif that is characterized by its preference for binding to AT-rich regions of DNA. It is a short amino acid motif composed of consecutive alanine-threonine (AT) residues, hence its name.
The AT hook motif is typically found in a variety of DNA-binding proteins, including transcription factors and architectural proteins. Its primary function is to interact with AT-rich regions within the double-stranded DNA helix, often resulting in the bending or distortion of the DNA structure. This bending capability plays a crucial role in regulating gene expression and chromatin structure.
The motif interacts with the minor groove of the DNA helix, where the AT-rich sequences tend to occur due to their decreased stability. By inserting its residues into the minor groove, the AT hook motif stabilizes the distorted DNA conformation and promotes the formation of protein-DNA complexes.
The AT hook motif is known for its ability to recognize and bind to specific AT-rich DNA sequences, typically consisting of four to nine AT base pairs. This sequence specificity contributes to the precise targeting of the AT hook motif-containing proteins to their respective DNA binding sites.
Overall, the AT hook motif represents a functional DNA-binding motif that selectively recognizes AT-rich regions of DNA, allowing for the modulation of gene expression and chromatin structure in various biological processes.
Common Misspellings for AT HOOK MOTIF
- zt hook motif
- st hook motif
- wt hook motif
- qt hook motif
- ar hook motif
- af hook motif
- ag hook motif
- ay hook motif
- a6 hook motif
- a5 hook motif
- at gook motif
- at book motif
- at nook motif
- at jook motif
- at uook motif
- at yook motif
- at hiok motif
- at hkok motif
- at hlok motif
- at hpok motif
Infographic
Add the infographic to your website:
