The word "Astroviridae" is spelled in accordance with the International Phonetic Alphabet (IPA) phonetic transcription. This is a system for transcribing the exact sounds found in any language. In this case, "Astroviridae" is spelled with the sounds "æstroʊvaɪ'raɪdiʌɪ". The hyphen is used to indicate that the emphasis is on the "vaɪ" syllable. Astroviridae is a family of RNA viruses that affect a wide range of mammals, including humans. They are usually associated with gastroenteritis.
Astroviridae is a family of small, nonenveloped, icosahedral viruses that belong to the order of Astrovirales. These viral particles are approximately 28-30 nanometers in diameter and composed of a single-stranded, positive-sense RNA genome enclosed within a protein capsid. Members of the Astroviridae family primarily infect vertebrates, including humans, as well as some avian and mammalian species.
Astroviridae viruses are known to cause various diseases, such as gastroenteritis in humans and diarrhea in animals, especially young ones. They are commonly found in fecal matter, and transmission occurs through the oral-fecal route, either via direct contact or ingestion of contaminated food and water. The viral particles primarily target the small intestine, causing inflammation and disruption of the normal functioning of the infected host.
The genome of Astroviridae viruses is relatively small, ranging from approximately 6.4 to 7.9 kilobases in size. It consists of three open reading frames (ORFs) that code for viral proteins involved in viral replication, assembly, and pathogenesis. The ORF1a and ORF1b encode nonstructural proteins essential for viral RNA synthesis, while the ORF2 encodes the capsid protein responsible for protecting the genetic material and facilitating viral entry into host cells.
Astroviridae viruses are classified into eight serotypes (1-8) based on capsid protein sequence differences. These serotypes display various degrees of host specificity and pathogenicity. Understanding the molecular and epidemiological aspects of Astroviridae viruses are crucial for developing effective diagnostic methods, antiviral therapies, and preventive measures to control their spread and mitigate their impact on human and animal health
The word "Astroviridae" is derived from the combination of two components: "astro" and "viridae".
The term "astro" comes from the Latin word "astrum", meaning "star". It is often used as a prefix in scientific terms to indicate a connection to stars or celestial objects.
The suffix "-viridae" is derived from the Latin word "virus", which means "slimy liquid, poison". In the field of virology, "viridae" is used to denote a family of viruses.
So, when combined, "Astroviridae" can be understood as a family of viruses with a name that suggests a connection to stars or celestial objects.