Aspidosamine is a chemical compound found in certain plants. The spelling of aspidosamine is based on the International Phonetic Alphabet (IPA) and can be pronounced as [æspɪdosəmiːn]. The phonetic transcription for the word helps to understand the sound of each letter and provides clarity in pronunciation. Aspidosamine is commonly used in the pharmaceutical industry as it has various medicinal properties. Proper spelling and pronunciation are essential in the scientific field as it ensures clear communication between researchers and professionals.
Aspidosamine is a noun that refers to a class of indole alkaloids derived from the plant genus Aspidosperma, commonly known as the aspidosperma plants or the Peruvian barks. These alkaloids are primarily found in the bark of these plants and possess specific medicinal properties.
Aspidosamine compounds have gained significant attention in the field of medicine due to their potent and diverse pharmacological activities. They exhibit distinct biological properties, including antitumor, antifungal, and antiparasitic effects. One of the well-known derivatives of aspidosamine is Vindesine, which has been extensively used in chemotherapy to treat various types of cancers.
These alkaloids work by interfering with cellular processes, particularly inhibiting the proliferation and growth of cancer cells. Aspidosamine derivatives have been found to bind to certain receptors, such as tubulin, which ultimately disrupts the microtubule formation and cell division. This mechanism makes them effective in impeding the growth and spread of cancerous cells.
Furthermore, aspidosamine compounds have also demonstrated significant antimalarial properties by blocking the development of Plasmodium falciparum, the parasite responsible for causing malaria. Studies have shown that these alkaloids effectively inhibit the parasite's multiplication, providing a potential alternative treatment for this life-threatening disease.
Overall, aspidosamine refers to a class of indole alkaloids derived from the aspidosperma plants, known for their unique pharmacological properties, including antitumor and antimalarial effects. Their potential in medicinal applications presents opportunities for further research and development in the field of pharmaceutical sciences.
A strong base, C22H28N2O2, derived from aspidosperma, or quebracho.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "aspidosamine" is derived from two main components: "aspidos" and "amine".
1. Aspidos: This component comes from the Greek word "aspidos", meaning "shield" or "round shield". It is derived from the word "aspis", which refers to a type of large, oval shield that was used in ancient Greece. "Aspidos" is often used in scientific terminology to describe various shield-shaped structures or organisms.
2. Amine: The term "amine" is derived from the suffix "-amine", which originated from the French word "amine" and was later influenced by the suffix "-amine" in Latin. It refers to a type of organic compound that contains a nitrogen atom bonded to one or more hydrogen atoms. Amines are an important class of substances in biology and chemistry.