How Do You Spell ARYLAMINE N ACETYLTRANSFERASE?

Pronunciation: [ɑːɹˈɪlɐmˌiːn ˈɛn ˈasɪtˌɪltɹɐnsfˌɜːɹe͡ɪz] (IPA)

The spelling of "Arylamine N Acetyltransferase" is complex, but can be broken down using the International Phonetic Alphabet (IPA). The first syllable, "Aryl", is pronounced /ˈærɪl/, with the stress on the first sound. The second syllable is pronounced /əˌmiːn/, with the stress on the second sound. The third syllable, "N", is pronounced /ɛn/. The fourth syllable, "Acetyl", is pronounced /əˈsiːtəl/, with the stress on the second sound. The final syllable, "transferase", is pronounced /ˈtrænsfəreɪz/, with the stress on the first sound.

ARYLAMINE N ACETYLTRANSFERASE Meaning and Definition

1. Arylamine N-acetyltransferase (NAT) is an enzyme found in humans and other organisms that is involved in the metabolism of certain drugs, chemicals, and toxins. It belongs to the acetyltransferase family of enzymes, which are responsible for transferring an acetyl group from acetyl-CoA (a small molecule involved in cellular metabolism) to other molecules.

   Arylamine N-acetyltransferase specifically acts on arylamines, which are organic compounds containing an aromatic ring and an amino group. It plays a crucial role in the detoxification process by catalyzing the acetylation of arylamines, converting them into their corresponding N-acetylarylamine metabolites. This acetylation reaction helps to make the arylamines more water-soluble, facilitating their elimination from the body through urine.

   In addition to drug metabolism, arylamine N-acetyltransferase is also involved in other important cellular processes, including DNA repair and the regulation of apoptosis (programmed cell death). Variations in the NAT gene can lead to differences in enzyme activity, which can affect an individual's ability to metabolize certain drugs and may contribute to differences in drug efficacy and toxicity among different individuals.

   Understanding the function and variations of arylamine N-acetyltransferase is important for personalized medicine, as it can help predict an individual's response to certain drugs and aid in drug development and dosage adjustments for optimal therapeutic outcomes.

Common Misspellings for ARYLAMINE N ACETYLTRANSFERASE

• zrylamine n acetyltransferase
• srylamine n acetyltransferase
• wrylamine n acetyltransferase
• qrylamine n acetyltransferase
• aeylamine n acetyltransferase
• adylamine n acetyltransferase
• afylamine n acetyltransferase
• atylamine n acetyltransferase
• a5ylamine n acetyltransferase
• a4ylamine n acetyltransferase
• artlamine n acetyltransferase
• arglamine n acetyltransferase
• arhlamine n acetyltransferase
• arulamine n acetyltransferase
• ar7lamine n acetyltransferase
• ar6lamine n acetyltransferase
• arykamine n acetyltransferase
• arypamine n acetyltransferase
• aryoamine n acetyltransferase
• arylzmine n acetyltransferase