ARA A Meaning and
Definition
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Ara A is a term used in the field of biological sciences, particularly in cell culture research and molecular biology. It refers to a potent and highly selective antineoplastic agent or chemotherapy drug that belongs to the group of nucleoside analogues. Ara A is an abbreviation for "adenine arabinoside" where "adenine" represents the nucleobase and "arabinoside" indicates the sugar component of the molecule.
As a nucleoside analogue, Ara A is structurally similar to the naturally occurring nucleosides, in this case, adenine, found in DNA and RNA. However, Ara A is modified in such a way that it is incorporated into the DNA or RNA of replicating cells, leading to the termination of DNA chain elongation or RNA synthesis. This disruption inhibits cell proliferation and ultimately induces cell death.
Ara A has demonstrated broad-spectrum antiviral and antitumor activities. It has been extensively used in scientific research to study the mechanisms of DNA replication, transcription, and translation. Additionally, Ara A has shown clinical efficacy against various malignant tumors, including leukemia and lymphomas. However, its use is often limited due to its narrow therapeutic index and potential side effects, such as bone marrow suppression and gastrointestinal disturbances.
In summary, Ara A is a potent antineoplastic agent that acts by interfering with DNA and RNA synthesis, thereby inhibiting cell proliferation. Its clinical and research applications focus on treating certain types of cancers and studying fundamental cellular processes.
Common Misspellings for ARA A
- ara aq
- raa a
- aar a
- ar aa
- aara a
- arra a
- araa a
- ara a
- ara aa
- ira A
- era A
- cra A
- A2a A
- Aba A
- Aza A
- Apa A
- Ara0A
- Ara c
- a ra a
- ar a a
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