APUD CELL Meaning and
Definition
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The term "APUD cell" refers to a specialized type of neuroendocrine cell found in various body tissues and organs. APUD stands for "amine precursor uptake and decarboxylation," which highlights the distinctive characteristics of these cells.
APUD cells are known for their unique ability to take up and convert amine precursor molecules into active amine neurotransmitters or hormones. They accomplish this by utilizing specific transport proteins to capture precursor molecules from the bloodstream and subsequently decarboxylating them into the active form.
These cells are found in several organs, including the brain, the gastrointestinal tract, the lungs, and various endocrine glands. They play a crucial role in the regulation and control of several physiological processes, such as the coordination of neural signals, modulation of hormone release, and overall homeostasis.
The importance of APUD cells is further emphasized by their role in certain diseases. For instance, abnormalities in APUD cell functioning have been implicated in the development of neuroendocrine tumors, such as carcinoid tumors and small cell lung cancer.
In summary, APUD cell represents a specialized neuroendocrine cell that is characterized by its ability to uptake amine precursor molecules and convert them into active amine neurotransmitters or hormones. Through this unique function, APUD cells contribute to the regulation of various physiological processes and can be involved in the development of certain diseases.
Common Misspellings for APUD CELL
- zpud cell
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- aoud cell
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- apyd cell
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- apue cell
Etymology of APUD CELL
The term "APUD cell" is a specialized medical term that is derived from Latin. It is an acronym for "Amine Precursor Uptake and Decarboxylation" (APUD).
The concept of APUD cells was first introduced in the mid-20th century by a British pathologist named Albert Coons. Coons discovered that certain cells in the body have the ability to take up precursor molecules (such as an amino acid) and convert them into active hormones or neurotransmitters via a process called decarboxylation. These cells were primarily found in the endocrine system, specifically in organs such as the gastrointestinal tract, lungs, and thyroid.
To name these specific cells, Coons coined the term "APUD cells" by combining the first letters of the process (Amine Precursor Uptake and Decarboxylation) with the word "cell".
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