APOPROTEIN B Meaning and
Definition
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Apoprotein B (ApoB) is a type of protein molecule that plays a crucial role in cholesterol metabolism and lipid transportation in the body. It is primarily produced by the liver and is the main structural component of low-density lipoproteins (LDL), also known as "bad cholesterol."
With around 4536 amino acids, ApoB is one of the largest proteins found in the human body. It acts as a ligand or binder for LDL receptors, allowing the transportation of cholesterol-rich lipoproteins from the liver to peripheral tissues throughout the body. ApoB functions as a carrier protein, holding together the lipid molecules within LDL particles.
The ApoB protein molecule can exist in two forms: ApoB-48 and ApoB-100. ApoB-48 is a shorter version of the protein primarily synthesized by the intestine. It is involved in the transport of dietary fats from the intestines to other tissues. ApoB-100, on the other hand, is produced by the liver and is involved in the assembly and secretion of very-low-density lipoproteins (VLDL), which are later converted into LDL.
Elevated levels of ApoB or abnormalities in its structure have been associated with an increased risk of cardiovascular diseases, as they contribute to the accumulation of cholesterol in arterial walls, leading to atherosclerosis and potentially heart disease. Therefore, ApoB is often measured as a marker of LDL metabolism and cardiovascular risk assessment.
Common Misspellings for APOPROTEIN B
- apoproteinb
- zpoprotein b
- spoprotein b
- wpoprotein b
- qpoprotein b
- aooprotein b
- aloprotein b
- a-oprotein b
- a0oprotein b
- apiprotein b
- apkprotein b
- aplprotein b
- appprotein b
- ap0protein b
- ap9protein b
- apoorotein b
- apolrotein b
- apo-rotein b
- apo0rotein b
- apopeotein b
Etymology of APOPROTEIN B
The word "Apoprotein B" is derived from Greek and Latin roots.
The term "Apo" comes from the Greek word "απο", meaning "away from" or "off". In scientific terminology, "apo" is commonly used to denote a protein from which a smaller molecule or other group has been removed.
The word "protein" originates from the Greek word "πρωτεῖον" (proteion), which means "primary" or "of primary importance". It refers to large, complex molecules that are essential for the structure and function of cells and tissues in living organisms.
The letter "B" in "Apoprotein B" refers to the second identified apoprotein in a specific class. Apoprotein B is actually an important type of apoprotein involved in protein-lipid interaction and transport.
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