APOLIPOPROTEINS A Meaning and
Definition
-
Apolipoproteins A, also known as apolipoprotein A, are a family of proteins that play a crucial role in lipid metabolism and transport within the human body. These proteins are primarily associated with high-density lipoproteins (HDL), which are commonly referred to as "good cholesterol."
Apolipoproteins A are synthesized in the liver and intestines, and their main function is to stabilize and regulate the metabolism of lipids. They accomplish this by binding to lipids and forming complexes known as lipoproteins. Specifically, apolipoproteins A associate with phospholipids and cholesterol to create HDL particles.
The key role of apolipoproteins A is to facilitate reverse cholesterol transport (RCT). This process involves the removal of excess cholesterol from peripheral tissues and its transport back to the liver for excretion or recycling. By binding to cholesterol and other lipids, these apolipoproteins help HDL particles to efficiently transport those lipids to the liver.
Moreover, apolipoproteins A are involved in various other biological processes, such as antioxidative activity, regulation of cellular lipid homeostasis, modulation of immune responses, and anti-inflammatory effects. They also participate in the activation and inhibition of enzymes that regulate lipid metabolism.
Alterations or deficiencies in apolipoproteins A have been associated with increased risk factors for cardiovascular diseases, including atherosclerosis and coronary artery disease. Consequently, studying the levels and functionality of these apolipoproteins aids in assessing an individual's cardiovascular health status and may guide the development of therapeutic strategies targeting lipid metabolism disorders.
Common Misspellings for APOLIPOPROTEINS A
- zpolipoproteins a
- spolipoproteins a
- wpolipoproteins a
- qpolipoproteins a
- aoolipoproteins a
- alolipoproteins a
- a-olipoproteins a
- a0olipoproteins a
- apilipoproteins a
- apklipoproteins a
- apllipoproteins a
- applipoproteins a
- ap0lipoproteins a
- ap9lipoproteins a
- apokipoproteins a
- apopipoproteins a
- apooipoproteins a
- apolupoproteins a
- apoljpoproteins a
- apolkpoproteins a
Etymology of APOLIPOPROTEINS A
The word "Apolipoproteins A" is derived from Greek and is composed of three elements: "apo-", meaning "away" or "from", "lipo", meaning "fat" or "lipid", and "protein", denoting a type of biomolecule consisting of amino acids.
To further break it down, "apo" in this context refers to the function of apolipoproteins, which are proteins that bind with lipids to form lipoproteins. "Lipo" is related to the fact that lipoproteins carry fats and cholesterol in the blood. The inclusion of "protein" indicates that this term specifically refers to a class of proteins.
The suffix "A" is likely used to distinguish different subtypes of apolipoprotein by assigning a letter or number to them. In this case, "A" indicates a specific subtype of apolipoprotein.
Infographic
Add the infographic to your website:
