APCI Meaning and
Definition
-
APCI stands for Atmospheric Pressure Chemical Ionization. It is a technique used in mass spectrometry, a powerful analytical tool used in various scientific disciplines. APCI is a method of ionization that allows the analysis of a wide range of compounds, particularly those that are nonpolar and thermally labile.
In APCI, the sample is introduced into the mass spectrometer via a nebulizer or a vaporizer at atmospheric pressure. The sample is then sprayed into a heated vaporization chamber where it becomes a fine mist or aerosol. The aerosol is then mixed with a spray of reagent ions, typically in the form of a low-energy corona discharge, in order to induce ionization.
The ionized sample molecules are then directed into the mass spectrometer through a series of ion optics and separated based on their mass-to-charge ratio. They are then detected by a mass analyzer, which provides valuable information about the chemical composition, structure, and abundance of the sample.
APCI is particularly useful for the analysis of nonvolatile and thermally labile compounds, as it eliminates the need for sample evaporation and thermal desorption. It also allows the detection of compounds with low ionization potentials and those that are not amenable to other ionization methods like electron ionization. APCI is therefore widely used in areas such as pharmaceuticals, environmental analysis, and metabolomics, where the identification and quantification of complex mixtures of compounds are essential.
Common Misspellings for APCI
- apcij
- apcki
- apcik
- apcoi
- apcio
- apc9i
- apci9
- apc8i
- apci8
- aapci
- appci
- apcci
- apcii
- APgI
- APbI
- APCy
- apc i
Infographic
Add the infographic to your website:
