ANTIREJECTION DRUG Meaning and
Definition
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An antirejection drug, also known as an immunosuppressant medication, refers to a pharmaceutical substance or class of medications primarily used to prevent the rejection of organ or tissue transplants by the recipient's immune system. These drugs act by suppressing the immune response in order to allow transplanted organs or tissues to be accepted and integrated without significant inflammation or rejection.
When an organ or tissue is transplanted, the body's immune system recognizes it as foreign and triggers an immune response aimed at eliminating the "intruder." Antirejection drugs help modulate the immune system's response by reducing its ability to mount an aggressive attack against the transplanted organ or tissue. By suppressing certain immune responses, these medications attenuate various immune cell activities, such as T-cell proliferation and cytokine production, which are essential for rejection.
Antirejection drugs are typically prescribed following organ transplantation, such as kidney, heart, liver, or lung transplants. They are usually administered orally or intravenously, and the dosage is carefully monitored and adjusted to achieve an optimal balance between immunosuppression and the risk of side effects. Common examples of antirejection drugs include corticosteroids, calcineurin inhibitors (such as cyclosporine or tacrolimus), and mTOR inhibitors (such as sirolimus or everolimus).
While these medications are crucial for successful transplantation, they also increase the recipient's susceptibility to infections and other potential adverse effects. Therefore, close monitoring of the individual's immunological status and comprehensive medical supervision are necessary during treatment with antirejection drugs.
Common Misspellings for ANTIREJECTION DRUG
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Etymology of ANTIREJECTION DRUG
The term "antirejection drug" is a compound term formed from the combination of the prefix "anti-", which means against or opposed to, and the word "rejection". The word "rejection" refers to the process where the immune system identifies a foreign substance, such as an organ transplant, and responds by attacking or rejecting it.
The word "drug" in this context refers to a medication or substance used to treat, prevent, or manage a specific condition. Therefore, an "antirejection drug" is a medication designed to prevent or suppress the rejection of a transplanted organ by the recipient's immune system. These drugs are used to minimize the immune response to the foreign organ, allowing for successful transplantation and long-term organ function.
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