ANTIHAEMOPHILIC GLOBULIN Meaning and
Definition
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Antihaemophilic globulin, also known as Factor VIII, is a protein required for normal blood clotting. It plays a crucial role in the clotting cascade, a series of biochemical reactions that occur when a blood vessel is damaged to prevent excessive bleeding. Antihaemophilic globulin is primarily produced in special cells called endothelial cells, which line the blood vessels, as well as in the liver.
Deficiency in antihaemophilic globulin leads to a medical condition called haemophilia A, which is characterized by a reduced ability to form blood clots. Haemophilia A is an inherited disorder, caused by mutations in the gene that produces antihaemophilic globulin. Individuals with haemophilia A may experience prolonged bleeding after minor injuries or surgeries and may also have spontaneous bleeding into joints or muscles.
To treat haemophilia A, antihaemophilic globulin can be administered intravenously to temporarily replace the missing protein. This therapy, known as replacement therapy, is especially important during episodes of bleeding or medical procedures to prevent life-threatening complications. Antihaemophilic globulin can be obtained from human blood plasma or produced through genetic engineering techniques using recombinant DNA technology.
Although the use of antihaemophilic globulin has significantly improved the quality of life for individuals with haemophilia A, it is important that the treatment is carefully monitored due to the risk of developing neutralizing antibodies against the administered protein, known as inhibitors. Inhibitors can reduce the effectiveness of replacement therapy, making it more challenging to control bleeding episodes.
Common Misspellings for ANTIHAEMOPHILIC GLOBULIN
- zntihaemophilic globulin
- sntihaemophilic globulin
- wntihaemophilic globulin
- qntihaemophilic globulin
- abtihaemophilic globulin
- amtihaemophilic globulin
- ajtihaemophilic globulin
- ahtihaemophilic globulin
- anrihaemophilic globulin
- anfihaemophilic globulin
- angihaemophilic globulin
- anyihaemophilic globulin
- an6ihaemophilic globulin
- an5ihaemophilic globulin
- antuhaemophilic globulin
- antjhaemophilic globulin
- antkhaemophilic globulin
- antohaemophilic globulin
- ant9haemophilic globulin
Etymology of ANTIHAEMOPHILIC GLOBULIN
The word "Antihaemophilic Globulin" is derived from a combination of multiple words.
1. Anti-: It comes from the Greek word "anti", meaning "against" or "opposite".
2. Haemophilic: This word is based on the medical condition "hemophilia", which is a bleeding disorder characterized by the inability of blood to clot properly. "Haemophilic" refers to something related to or associated with hemophilia.
3. Globulin: Globulin is a term used in biochemistry to refer to a group of proteins found in the blood plasma. They play various roles, including helping with blood clotting.
Thus, "Antihaemophilic Globulin" literally means a type of globulin protein that acts against or counters the effects of hemophilia, helping in blood clotting.
Similar spelling word for ANTIHAEMOPHILIC GLOBULIN
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