ANTICANCER DRUG SENSITIVITY TESTS Meaning and
Definition
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Anticancer Drug Sensitivity Tests refer to laboratory procedures aimed at determining the effectiveness of different cancer treatments or drugs (commonly known as chemotherapy) on an individual's cancer cells or tumor. These tests are conducted to assess how susceptible a patient's cancer cells are to specific medications or combinations of drugs, enabling healthcare professionals to make more informed decisions about treatment options.
The process typically involves extracting cancer cells from a patient (either through a biopsy or a blood sample), which are then grown in a controlled laboratory environment. These cells are subsequently exposed to various anticancer drugs at different concentrations to observe how well they respond. The response can be measured in multiple ways, such as assessing cell growth inhibition rates, determining cell death or apoptosis rates, or evaluating changes in biomarkers associated with cancer progression.
The information generated from these sensitivity tests provides valuable insights into which drugs or combinations of drugs offer the highest potential for therapeutic success in fighting the patient's specific cancer type. It aids healthcare professionals in selecting personalized treatment strategies, improves treatment efficacy, reduces adverse effects, and may even help predict treatment outcomes.
Although anticancer drug sensitivity tests are not commonly used in regular clinical practice, they hold great promise in guiding precision medicine approaches and advancing personalized cancer treatment. Ongoing research efforts are focused on refining these tests, increasing their accuracy, standardizing protocols, and ultimately integrating them into routine clinical care to enhance the overall outcomes for cancer patients.
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