ANNULATION Meaning and
Definition
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Annulation is a term used in chemistry and organic chemistry to describe a process in which two or more rings are fused together to form a larger ring structure. It is derived from the Latin word "annulus," meaning ring. In annulation, the rings are connected by sharing two adjacent atoms, usually carbon atoms.
The process of annulation involves the formation of new bonds between the atoms that form the bridged carbons of the fused rings. This can occur through various chemical reactions, such as cyclization, where a portion of a molecule becomes a ring, or through substitution reactions, where one group is replaced by a different group.
Annulation plays a significant role in the synthesis of complex organic molecules and pharmaceuticals. It provides a versatile and powerful strategy for creating diverse ring systems and structural motifs, leading to the discovery of novel compounds with beneficial biological activities.
The technique of annulation enables chemists to access a wide range of ring sizes, giving them the ability to design and construct complex molecular architectures. By manipulating the reaction conditions, such as temperature, solvent, and catalyst, specific ring sizes and arrangements can be achieved. This allows scientists to tailor the properties and functionalities of the synthesized compounds according to desired applications.
In summary, annulation is the process of fusing two or more rings together, forming a larger ring structure. It is a crucial approach in organic synthesis and plays a vital role in the creation of novel molecules with useful properties.
Common Misspellings for ANNULATION
Etymology of ANNULATION
The word "annulation" originates from the Latin term "annulatio", which is derived from the verb "annulare", meaning "to make null or invalid". This Latin word, in turn, is derived from the noun "annulus", meaning "ring" or "circle". Over time, "annulation" developed to refer to the act of nullifying or invalidating something, often in legal or official contexts.
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